دورية أكاديمية

[Survey on drug resistance to ciprofloxacin in common pathogenic bacteria].

التفاصيل البيبلوغرافية
العنوان: [Survey on drug resistance to ciprofloxacin in common pathogenic bacteria].
المؤلفون: Zhang YL; Department of Infection Control, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China., Geng SN, Lai FC, Wang NP
المصدر: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA [Di Yi Jun Yi Da Xue Xue Bao] 2002 Apr; Vol. 22 (4), pp. 378-9.
نوع المنشور: English Abstract; Journal Article
اللغة: Chinese
بيانات الدورية: Publisher: Di 1 jun yi da xue Country of Publication: China NLM ID: 9426110 Publication Model: Print Cited Medium: Print ISSN: 1000-2588 (Print) Linking ISSN: 10002588 NLM ISO Abbreviation: Di Yi Jun Yi Da Xue Xue Bao Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Guangzhou Shi Tonghe Zhen : Di 1 jun yi da xue, -2005.
مواضيع طبية MeSH: Anti-Infective Agents/*pharmacology , Ciprofloxacin/*pharmacology , Drug Resistance, Bacterial/*physiology , Enterococcus/*drug effects , Staphylococcus/*drug effects, Data Collection ; Microbial Sensitivity Tests
مستخلص: Objective: To obtain primary knowledge of drug resistance to ciprofloxacin in the common pathogenic bacteria in this hospital thereby to bring the situation under control.
Methods: A total of 3 800 strains of pathogenic bacteria were isolated from in-patients from 1997 to 2000, and drug resistance of these strains to ciprofloxacin was examined.
Results: During the past 4 years, Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalis were found to be highly resistant to ciprofloxacin with the rates still on the rise from 50%, 25.6% and 40.3% in 1997 to 62.2%, 53.4% and 63.6% respectively in 2000. Over 40% of Escherichia coli, Klebsiella pneumoniae and Enterobacter were resistant to ciprofloxacin and the percentages for Pseudomonas aeruginosa and Acinetobacter reached 31.1% to 34.0% in 2000. Among the 189 strains of the pathogenic bacteria isolated from patients with sustained infection in our hospital in 2000, over 70% of Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalis were identified as having resistance to ciprofloxacin.
Conclusion: The percentages of common pathogenic bacteria that are resistant to ciprofloxacin have been considerably high and tend to increase further. Ciprofloxacin abuse needs to be given appropriate attention.
المشرفين على المادة: 0 (Anti-Infective Agents)
5E8K9I0O4U (Ciprofloxacin)
تواريخ الأحداث: Date Created: 20021023 Date Completed: 20021119 Latest Revision: 20131121
رمز التحديث: 20221213
PMID: 12390755
قاعدة البيانات: MEDLINE