دورية أكاديمية
[Evaluation of preservation and the collagen structure state in the mummy tissues].
العنوان: | [Evaluation of preservation and the collagen structure state in the mummy tissues]. |
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عنوان ترانسليتريتد: | Otsenka sokhrannosti i sostoianiia kollagenovykh struktur v tkaniakh mumii. |
المؤلفون: | Romakov IuA; Scientific Research and Edi Cantrol Center of Biomedical Technologies, 123056, Moscow., Bykov VA, Rebrova GA, Vasilevskiĭ VK, Ho SS, Rebrov LB |
المصدر: | Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Jul-Aug; Vol. 48 (4), pp. 357-60. |
نوع المنشور: | English Abstract; Journal Article |
اللغة: | Russian |
بيانات الدورية: | Publisher: Rossiĭskai︠a︡ Akademii︠a︡ Medit︠s︡inskikh Nauk Country of Publication: Russia (Federation) NLM ID: 0416601 Publication Model: Print Cited Medium: Print ISSN: 0042-8809 (Print) Linking ISSN: 00428809 NLM ISO Abbreviation: Vopr Med Khim Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Moskva : Rossiĭskai︠a︡ Akademii︠a︡ Medit︠s︡inskikh Nauk Original Publication: Moskva. |
مواضيع طبية MeSH: | Mummies*, Collagen/*chemistry, Bone and Bones/chemistry ; Endopeptidases/chemistry ; Humans ; Hydrolysis ; Muscle, Skeletal/chemistry ; Skin/chemistry ; Solubility |
مستخلص: | The content and state of collagen in skin, muscle and bone of 2500-year-old Altai mummies were studied. Collagen is the predominant protein in studied tissues of the mummies. High degree of the resistance of collagen to the effect of various proteases (collagenase, pronase, pepsin) and to alkline and acidic hydrolysis suggests on the considerable chemical modification of tissue collagen structures of the mummy. The possibility of increased collagen cross-linkages in tissues of the mummies during long-term storage and of nonenzymatic glycosylation of collagen leading to the formation an Amadori products and other modified structures are discussed. |
المشرفين على المادة: | 9007-34-5 (Collagen) EC 3.4.- (Endopeptidases) |
تواريخ الأحداث: | Date Created: 20030101 Date Completed: 20030410 Latest Revision: 20061115 |
رمز التحديث: | 20240627 |
PMID: | 12506610 |
قاعدة البيانات: | MEDLINE |
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