دورية أكاديمية
[Follicle stimulating hormone as predictor of mobile spermatozoa in testicular biopsy of azoospermic patients].
| العنوان: | [Follicle stimulating hormone as predictor of mobile spermatozoa in testicular biopsy of azoospermic patients]. |
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| عنوان ترانسليتريتد: | Hormônio folículo estimulante como preditor do achado de espermatozóides móveis na biópsia testicular de casos de azoospermia. |
| المؤلفون: | de Souza CA; Setor de Reprodução Assistida / Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil. casouza@via-rs.net, Cunha Filho JS, Santos D, Gratão AA, Filippon L, Tedesco C, Freitas F, Passos EP |
| المصدر: | Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2003 Apr-Jun; Vol. 49 (2), pp. 167-72. Date of Electronic Publication: 2003 Jul 22. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Portuguese |
| بيانات الدورية: | Publisher: Associação Médica Brasileira Country of Publication: Brazil NLM ID: 9308586 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0104-4230 (Print) Linking ISSN: 01044230 NLM ISO Abbreviation: Rev Assoc Med Bras (1992) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo : Associação Médica Brasileira |
| مواضيع طبية MeSH: | Sperm Motility*, Follicle Stimulating Hormone/*blood , Oligospermia/*blood , Testis/*pathology, Adult ; Analysis of Variance ; Biomarkers/blood ; Biopsy ; Cross-Sectional Studies ; Humans ; Male ; Oligospermia/pathology ; Prognosis ; Prolactin/blood ; Sensitivity and Specificity ; Sperm Count ; Testosterone/blood |
| مستخلص: | Objective: To define predictive factors of mobile spermatozoa recovery in azoospermic patients. Methods: Testicular volume, serum follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL) and testosterone levels were assessed in 60 azoospermic patients. Patients underwent bilateral testicular biopsy with local anesthesia. Samples were classified according to absence of spermatozoa, presence of motile and nonmotile spermatozoa, and histological findings. Age, hormone levels, testicular volume and histology with motile spermatozoa recovery were compared. P < 0.05 was considered significant. Results: Non-obstructive azoospermia was diagnosed in 45 patients. Significant differences were detected between the group with motile spermatozoa recovery and the group with absence of spermatozoa in terms of FSH levels (P=0.037 ANOVA one-way). A ROC curve was used to define FSH values below 16.05 IU/L (sensitivity: 76.2%, specificity: 67.7%) as predictive factors for motile spermatozoa recovery. Other statistical differences were not detected. Conclusions: FSH levels below 16.05 IU/L showed good accuracy to predict the presence of motile spermatozoa in the testicular biopsy of azoospermic patients. Physical examination, testosterone levels, LH and prolactin were not useful as predictive factors in the present study. |
| المشرفين على المادة: | 0 (Biomarkers) 3XMK78S47O (Testosterone) 9002-62-4 (Prolactin) 9002-68-0 (Follicle Stimulating Hormone) |
| تواريخ الأحداث: | Date Created: 20030730 Date Completed: 20031027 Latest Revision: 20160815 |
| رمز التحديث: | 20221213 |
| PMID: | 12886394 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0104-4230 |
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