دورية أكاديمية

[Prospective study of pregnants and babies with risk of congenital toxoplasmosis in municipal district of Rio Grande do Sul].

التفاصيل البيبلوغرافية
العنوان: [Prospective study of pregnants and babies with risk of congenital toxoplasmosis in municipal district of Rio Grande do Sul].
عنوان ترانسليتريتد: Estudo prospectivo de gestantes e seus bebês com risco de transmissão de toxoplasmose congênita em município do Rio Grande do Sul.
المؤلفون: Spalding SM; Laboratório Central do Estado, Secretaria da Saúde do Estado do Rio Grande do Sul, Fundação Estadual de Produção e Pesquisa em Saúde, Porto Alegre, RS, Brasil., Amendoeira MR, Ribeiro LC, Silveira C, Garcia AP, Camillo-Coura L
المصدر: Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2003 Jul-Aug; Vol. 36 (4), pp. 483-91. Date of Electronic Publication: 2003 Aug 13.
نوع المنشور: English Abstract; Journal Article
اللغة: Portuguese
بيانات الدورية: Publisher: Sociedade Brasileira de Medicina Tropical Country of Publication: Brazil NLM ID: 7507456 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0037-8682 (Print) Linking ISSN: 00378682 NLM ISO Abbreviation: Rev Soc Bras Med Trop Subsets: MEDLINE
أسماء مطبوعة: Publication: <1997-> : Uberaba, MG, Brazil : Sociedade Brasileira de Medicina Tropical
Original Publication: Rio De Janeiro : Sociedade Brasileira De Medicina Tropical
مواضيع طبية MeSH: Antibodies, Protozoan/*blood , Immunoglobulins/*blood , Pregnancy Complications, Parasitic/*epidemiology , Toxoplasmosis/*epidemiology, Animals ; Antibody Affinity ; Brazil/epidemiology ; Enzyme-Linked Immunosorbent Assay ; Epidemiologic Methods ; Female ; Fluorescent Antibody Technique, Indirect ; Humans ; Infant ; Infant, Newborn ; Infectious Disease Transmission, Vertical ; Male ; Mass Screening ; Mice ; Polymerase Chain Reaction ; Pregnancy ; Pregnancy Complications, Parasitic/blood ; Toxoplasmosis/diagnosis ; Toxoplasmosis/drug therapy ; Toxoplasmosis/transmission ; Toxoplasmosis, Congenital/diagnosis ; Toxoplasmosis, Congenital/epidemiology ; Toxoplasmosis, Congenital/prevention & control
مستخلص: This study followed up 2,126 pregnant women cared for at SUS day-care clinics (Public Health Insurance System) of the northwest of the State of Rio Grande do Sul, Brazil. After serological screening we performed a follow up of all pregnant women and their babies. Serologic tests included: IgG, IgM, IgA and IgG avidity levels, mice inoculation and polymerase chain reaction (PCR) also placentas and umbilical materials were tested using immunoperoxidase as well as clinical evaluation. Of all the pregnant women screened, 74.5% were reactive to toxoplasmosis, and 3.6% presented IgM seropositivity. At ophthalmic evaluation ten women had ocular lesions and one infant presented eye lesions and brain calcification. The presence of anti-T.gondii specific IgM throughout the entire pregnancy did not characterize acute phase infection, for this, complementary tests were necessary. The importance is underscored for attendance of the newborn of mothers presenting serology compatible with this infection even in the absence of signs and symptoms of congenital toxoplasmosis.
المشرفين على المادة: 0 (Antibodies, Protozoan)
0 (Immunoglobulins)
تواريخ الأحداث: Date Created: 20030826 Date Completed: 20031023 Latest Revision: 20220310
رمز التحديث: 20240829
DOI: 10.1590/s0037-86822003000400009
PMID: 12937726
قاعدة البيانات: MEDLINE
الوصف
تدمد:0037-8682
DOI:10.1590/s0037-86822003000400009