دورية أكاديمية
Syndrome of inappropriate secretion of antidiuretic hormone after infusional vincristine.
| العنوان: | Syndrome of inappropriate secretion of antidiuretic hormone after infusional vincristine. |
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| المؤلفون: | Escuro RS; Department of Medicine, Cleveland Metropolitan General Hospital, OH., Adelstein DJ, Carter SG |
| المصدر: | Cleveland Clinic journal of medicine [Cleve Clin J Med] 1992 Nov-Dec; Vol. 59 (6), pp. 643-4. |
| نوع المنشور: | Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cleveland Clinic Educational Foundation Country of Publication: United States NLM ID: 8703441 Publication Model: Print Cited Medium: Print ISSN: 0891-1150 (Print) Linking ISSN: 08911150 NLM ISO Abbreviation: Cleve Clin J Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Cleveland, OH] : Cleveland Clinic Educational Foundation, [c1987- |
| مواضيع طبية MeSH: | Antineoplastic Combined Chemotherapy Protocols/*adverse effects , Inappropriate ADH Syndrome/*chemically induced , Multiple Myeloma/*drug therapy , Vincristine/*adverse effects, Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Dexamethasone/administration & dosage ; Dexamethasone/adverse effects ; Doxorubicin/administration & dosage ; Doxorubicin/adverse effects ; Female ; Humans ; Infusions, Intravenous ; Vincristine/administration & dosage |
| مستخلص: | A 77-year-old woman with refractory multiple myeloma was treated with a 4-day continuous intravenous infusion of vincristine and doxorubicin and 4 days of oral dexamethasone. Nine days after her second cycle she presented with lethargy and weakness associated with hyponatremia. Evaluation revealed the syndrome of inappropriate secretion of antidiuretic hormone, which was attributed to the vincristine infusion. After normal serum sodium levels returned, further doxorubicin and dexamethasone chemotherapy without vincristine did not produce this complication. |
| المشرفين على المادة: | 5J49Q6B70F (Vincristine) 7S5I7G3JQL (Dexamethasone) 80168379AG (Doxorubicin) |
| SCR Protocol: | VAD I protocol |
| تواريخ الأحداث: | Date Created: 19921101 Date Completed: 19921221 Latest Revision: 20190902 |
| رمز التحديث: | 20240829 |
| DOI: | 10.3949/ccjm.59.6.643 |
| PMID: | 1424076 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0891-1150 |
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| DOI: | 10.3949/ccjm.59.6.643 |