دورية أكاديمية
Development of chemical sensors based on redox-dependent receptors: N,N'-dimethyldiazapyrenium-modified electrodes.
| العنوان: | Development of chemical sensors based on redox-dependent receptors: N,N'-dimethyldiazapyrenium-modified electrodes. |
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| المؤلفون: | Lilienthal ND; Department of Chemistry, San Diego State University, San Diego, California 92182-1030, USA., Alsafar H, Conerty J, Fernandez R, Kong C, Smith DK |
| المصدر: | Analytical chemistry [Anal Chem] 2003 Jul 15; Vol. 75 (14), pp. 3322-8. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print Cited Medium: Print ISSN: 0003-2700 (Print) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, American Chemical Society. |
| مستخلص: | Electrodes modified with Nafion films containing 2,7-dimethyldiazapyrenium (DAP2+) were prepared and characterized with voltammetry by themselves and in the presence of organic substrates. The large, planar, electron-poor aromatic surface in DAP2+ facilitates pi-stacking interactions with other planar aromatic molecules, particularly those that are negatively charged or electron-rich. Previous studies showed that the reduction of DAP2+ decreases the strength of these interactions, making the binding redox-dependent, and resulting in negative shifts in the E(1/2) of DAP2+/+. This study shows that the redox-dependent binding ability of DAP2+ is retained in Nafion, but the selectivity is considerably different. Most significantly, the electron-rich, neutral aromatic compounds that produced small shifts in the E(1/2) of DAP2+/+ in solution cause much larger shifts, up to -110 mV, with the modified electrodes. With indole as a substrate, Nernstian behavior is observed (-60 mV shift per log[indole]) between 10 and 0.5 mM. |
| تواريخ الأحداث: | Date Created: 20031023 Date Completed: 20040416 Latest Revision: 20190717 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1021/ac034234n |
| PMID: | 14570180 |
| قاعدة البيانات: | MEDLINE |
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