دورية أكاديمية

Phylogeography of Y-chromosome haplogroup I reveals distinct domains of prehistoric gene flow in europe.

التفاصيل البيبلوغرافية
العنوان: Phylogeography of Y-chromosome haplogroup I reveals distinct domains of prehistoric gene flow in europe.
المؤلفون: Rootsi S; Department of Evolutionary Biology, University of Tartu and Estonian Biocentre, Riia, Tartu, Estonia. sroots@ebc.ee, Magri C, Kivisild T, Benuzzi G, Help H, Bermisheva M, Kutuev I, Barać L, Pericić M, Balanovsky O, Pshenichnov A, Dion D, Grobei M, Zhivotovsky LA, Battaglia V, Achilli A, Al-Zahery N, Parik J, King R, Cinnioğlu C, Khusnutdinova E, Rudan P, Balanovska E, Scheffrahn W, Simonescu M, Brehm A, Goncalves R, Rosa A, Moisan JP, Chaventre A, Ferak V, Füredi S, Oefner PJ, Shen P, Beckman L, Mikerezi I, Terzić R, Primorac D, Cambon-Thomsen A, Krumina A, Torroni A, Underhill PA, Santachiara-Benerecetti AS, Villems R, Semino O
المصدر: American journal of human genetics [Am J Hum Genet] 2004 Jul; Vol. 75 (1), pp. 128-37. Date of Electronic Publication: 2004 May 25.
نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0002-9297 (Print) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE
أسماء مطبوعة: Publication: 2008- : [Cambridge, MA] : Cell Press
Original Publication: Baltimore, American Society of Human Genetics.
مواضيع طبية MeSH: Genetic Variation* , Geography* , Phylogeny* , Polymorphism, Genetic*, Chromosomes, Human, Y/*genetics , Haplotypes/*genetics, Africa, Northern ; Alleles ; Europe ; Gene Frequency ; Humans ; Male ; Mediterranean Region ; Microsatellite Repeats ; Middle East ; Multivariate Analysis ; Recombination, Genetic
مستخلص: To investigate which aspects of contemporary human Y-chromosome variation in Europe are characteristic of primary colonization, late-glacial expansions from refuge areas, Neolithic dispersals, or more recent events of gene flow, we have analyzed, in detail, haplogroup I (Hg I), the only major clade of the Y phylogeny that is widespread over Europe but virtually absent elsewhere. The analysis of 1,104 Hg I Y chromosomes, which were identified in the survey of 7,574 males from 60 population samples, revealed several subclades with distinct geographic distributions. Subclade I1a accounts for most of Hg I in Scandinavia, with a rapidly decreasing frequency toward both the East European Plain and the Atlantic fringe, but microsatellite diversity reveals that France could be the source region of the early spread of both I1a and the less common I1c. Also, I1b*, which extends from the eastern Adriatic to eastern Europe and declines noticeably toward the southern Balkans and abruptly toward the periphery of northern Italy, probably diffused after the Last Glacial Maximum from a homeland in eastern Europe or the Balkans. In contrast, I1b2 most likely arose in southern France/Iberia. Similarly to the other subclades, it underwent a postglacial expansion and marked the human colonization of Sardinia approximately 9,000 years ago.
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معلومات مُعتمدة: P01 GM028428 United States GM NIGMS NIH HHS
تواريخ الأحداث: Date Created: 20040527 Date Completed: 20040720 Latest Revision: 20220317
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC1181996
DOI: 10.1086/422196
PMID: 15162323
قاعدة البيانات: MEDLINE
الوصف
تدمد:0002-9297
DOI:10.1086/422196