دورية أكاديمية
Impact of medication adherence on hospitalization risk and healthcare cost.
| العنوان: | Impact of medication adherence on hospitalization risk and healthcare cost. |
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| المؤلفون: | Sokol MC; Department of Medical Affairs, Medco Health Solutions, Inc., Franklin Lakes, New Jersey 07417, USA., McGuigan KA, Verbrugge RR, Epstein RS |
| المصدر: | Medical care [Med Care] 2005 Jun; Vol. 43 (6), pp. 521-30. |
| نوع المنشور: | Evaluation Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0230027 Publication Model: Print Cited Medium: Print ISSN: 0025-7079 (Print) Linking ISSN: 00257079 NLM ISO Abbreviation: Med Care Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: Philadelphia, etc., Lippincott. |
| مواضيع طبية MeSH: | Chronic Disease/*drug therapy , Health Care Costs/*statistics & numerical data , Hospitalization/*statistics & numerical data , Patient Compliance/*statistics & numerical data , Self Administration/*statistics & numerical data, Adolescent ; Adult ; Child ; Child, Preschool ; Chronic Disease/economics ; Cohort Studies ; Comorbidity ; Drug Prescriptions ; Health Services/economics ; Health Services/statistics & numerical data ; Hospitalization/economics ; Humans ; Infant ; Infant, Newborn ; Insurance, Pharmaceutical Services ; Linear Models ; Middle Aged ; Retrospective Studies ; Self Administration/economics ; Treatment Outcome ; United States |
| مستخلص: | Objective: The objective of this study was to evaluate the impact of medication adherence on healthcare utilization and cost for 4 chronic conditions that are major drivers of drug spending: diabetes, hypertension, hypercholesterolemia, and congestive heart failure. Research Design: The authors conducted a retrospective cohort observation of patients who were continuously enrolled in medical and prescription benefit plans from June 1997 through May 1999. Patients were identified for disease-specific analysis based on claims for outpatient, emergency room, or inpatient services during the first 12 months of the study. Using an integrated analysis of administrative claims data, medical and drug utilization were measured during the 12-month period after patient identification. Medication adherence was defined by days' supply of maintenance medications for each condition. Patients: The study consisted of a population-based sample of 137,277 patients under age 65. Measures: Disease-related and all-cause medical costs, drug costs, and hospitalization risk were measured. Using regression analysis, these measures were modeled at varying levels of medication adherence. Results: For diabetes and hypercholesterolemia, a high level of medication adherence was associated with lower disease-related medical costs. For these conditions, higher medication costs were more than offset by medical cost reductions, producing a net reduction in overall healthcare costs. For diabetes, hypercholesterolemia, and hypertension, cost offsets were observed for all-cause medical costs at high levels of medication adherence. For all 4 conditions, hospitalization rates were significantly lower for patients with high medication adherence. Conclusions: For some chronic conditions, increased drug utilization can provide a net economic return when it is driven by improved adherence with guidelines-based therapy. |
| التعليقات: | Comment in: Med Care. 2005 Jun;43(6):517-20. (PMID: 15908845) |
| تواريخ الأحداث: | Date Created: 20050524 Date Completed: 20050623 Latest Revision: 20220410 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1097/01.mlr.0000163641.86870.af |
| PMID: | 15908846 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0025-7079 |
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| DOI: | 10.1097/01.mlr.0000163641.86870.af |