دورية أكاديمية
Myocardial ischemia induced by nebulized fenoterol for severe childhood asthma.
العنوان: | Myocardial ischemia induced by nebulized fenoterol for severe childhood asthma. |
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المؤلفون: | Zanoni LZ; Department of Pediatrics, Hospital Universitario, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil. Izzanoni@terra.com.br, Palhares DB, Consolo LC |
المصدر: | Indian pediatrics [Indian Pediatr] 2005 Oct; Vol. 42 (10), pp. 1013-8. |
نوع المنشور: | Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Indian Pediatrics Country of Publication: India NLM ID: 2985062R Publication Model: Print Cited Medium: Print ISSN: 0019-6061 (Print) Linking ISSN: 00196061 NLM ISO Abbreviation: Indian Pediatr Subsets: MEDLINE |
أسماء مطبوعة: | Publication: New Delhi : Indian Pediatrics Original Publication: Bombay. |
مواضيع طبية MeSH: | Asthma/*drug therapy , Bronchodilator Agents/*adverse effects , Fenoterol/*adverse effects , Myocardial Ischemia/*chemically induced, Administration, Inhalation ; Bronchodilator Agents/administration & dosage ; Child ; Child, Preschool ; Female ; Fenoterol/administration & dosage ; Humans ; Male ; Statistics, Nonparametric |
مستخلص: | We examined for myocardial ischemia induced by continuous inhalation of fenoterol in children with severe acute asthma. Thirty children with severe acute asthma were evaluated for signs of myocardial ischemia when treated with 0.5 mg kg dose (maximum 15 mg) of inhaled fenoterol for one hour. The heart rate was measured before and after inhalation. Cardiac enzymes (creatine kinase, creatine kinase MB fraction and troponin levels) were measured at admission and 12 hours later. An EKG was recorded before inhalation was started and immediately after its completion to detect the presence of any evidence of myocardial ischemia. All patients developed significant increase in heart rate. Six patients showed EKG changes compatible with myocardial ischemia, despite normal enzyme levels. Patients with severe acute asthma show tachycardia and may show EKG changes of myocardial ischemia. |
المشرفين على المادة: | 0 (Bronchodilator Agents) 22M9P70OQ9 (Fenoterol) |
تواريخ الأحداث: | Date Created: 20051105 Date Completed: 20051201 Latest Revision: 20131121 |
رمز التحديث: | 20221213 |
PMID: | 16269838 |
قاعدة البيانات: | MEDLINE |
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