دورية أكاديمية
Effect of artificial tears on visual acuity.
| العنوان: | Effect of artificial tears on visual acuity. |
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| المؤلفون: | Nilforoushan MR; Laser and Corneal Surgery Associates, PC, New York 10022, USA., Latkany RA, Speaker MG |
| المصدر: | American journal of ophthalmology [Am J Ophthalmol] 2005 Nov; Vol. 140 (5), pp. 830-5. |
| نوع المنشور: | Clinical Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print Cited Medium: Print ISSN: 0002-9394 (Print) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1999- : New York, NY : Elsevier Science Original Publication: [Chicago, etc., Ophthalmic Pub. Co., etc.] |
| مواضيع طبية MeSH: | Carboxymethylcellulose Sodium/*pharmacology , Dry Eye Syndromes/*drug therapy , Ophthalmic Solutions/*pharmacology , Visual Acuity/*drug effects, Aged ; Carboxymethylcellulose Sodium/administration & dosage ; Dry Eye Syndromes/physiopathology ; Female ; Humans ; Male ; Middle Aged ; Ophthalmic Solutions/administration & dosage ; Preservatives, Pharmaceutical ; Prospective Studies ; Tears/chemistry ; Tears/metabolism ; Visual Acuity/physiology |
| مستخلص: | Purpose: To study the effect of commonly used preservative free artificial tear, carboxymethylcellulose (CMC) 0.5% (Refresh Plus, Allergan, Irvine, California) on visual acuity in symptomatic dry eye (SDE) and asymptomatic dry eye (ADE) patients. Design: Nonrandomized prospective clinical trial. Methods: Prospective study involving 20 patients (40 eyes) with SDE and 20 patients (40 eyes) with ADE, all 40 years and older, were recruited from a clinic setting over a 1-month period. Distance visual acuity was measured by the Early Treatment of Diabetic Retinopathy Study (ETDRS) vision chart and near visual acuity was measured by the Lighthouse Near Vision chart before and 30 seconds after instillation of one drop of CMC. Distance and near visual acuity was measured both with and without correction. The duration of action of CMC was measured at 1-minute intervals until the patient's visual acuity returned to pretear level. Results: In both SDE and ADE groups, uncorrected and corrected near and distance vision showed a statistically significant improvement after the use of CMC (P < .05). There was no statistically significant difference in improvement between the SDE and ADE groups in all categories (P values > .05). The mean duration of improvement of vision was 2.93 minutes in the SDE group and 3.70 minutes in the ADE group (P = .036). Conclusions: CMC 0.5% provides a temporary yet significant improvement in the visual acuity of SDE and ADE patients. The effect of artificial tears on visual acuity may be of diagnostic value in detecting ocular surface abnormality in symptomatic and asymptomatic patients. |
| المشرفين على المادة: | 0 (Ophthalmic Solutions) 0 (Preservatives, Pharmaceutical) K679OBS311 (Carboxymethylcellulose Sodium) |
| تواريخ الأحداث: | Date Created: 20051129 Date Completed: 20051222 Latest Revision: 20161124 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1016/j.ajo.2005.05.001 |
| PMID: | 16310460 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0002-9394 |
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| DOI: | 10.1016/j.ajo.2005.05.001 |