دورية أكاديمية

Prevalence and antibiotic susceptibility of genital Mycoplasma hominis and Ureaplasma urealyticum in a university hospital in Turkey.

التفاصيل البيبلوغرافية
العنوان: Prevalence and antibiotic susceptibility of genital Mycoplasma hominis and Ureaplasma urealyticum in a university hospital in Turkey.
المؤلفون: Karabay O; Department of Infectious Diseases and Clinical Microbiology, Izzet Baysal Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey., Topcuoglu A, Kocoglu E, Gurel S, Gurel H, Ince NK
المصدر: Clinical and experimental obstetrics & gynecology [Clin Exp Obstet Gynecol] 2006; Vol. 33 (1), pp. 36-8.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: IMR Press Country of Publication: Singapore NLM ID: 7802110 Publication Model: Print Cited Medium: Print ISSN: 0390-6663 (Print) Linking ISSN: 03906663 NLM ISO Abbreviation: Clin Exp Obstet Gynecol Subsets: MEDLINE
أسماء مطبوعة: Publication: 2021- : Singapore : IMR Press
Original Publication: Padova : S.O.G
مواضيع طبية MeSH: Anti-Bacterial Agents/*pharmacology , Mycoplasma hominis/*drug effects , Ureaplasma urealyticum/*drug effects , Vaginal Discharge/*microbiology, Adolescent ; Adult ; Anti-Bacterial Agents/therapeutic use ; Cross-Sectional Studies ; Drug Resistance, Bacterial ; Female ; Hospitals ; Humans ; Microbial Sensitivity Tests ; Middle Aged ; Mycoplasma hominis/isolation & purification ; Turkey ; Ureaplasma urealyticum/isolation & purification
مستخلص: This study aimed to assess the colonization prevalence and antibiotic susceptibility of genital Ureaplasma urealyticum and Mycoplasma hominis in a teaching hospital, in Turkey. A total of 382 sexually active women with abnormal vaginal discharge were included in the study. Samples that were obtained with cotton swabs were microbiologically analyzed for U. urealyticum and M. hominis, together with antimicrobial susceptibility to doxycycline, ciprofloxacin, ofloxacin, erythromycin, josamycin, pristinamycin, and tetracycline. Ureaplasma urealyticum was detected in 185 (48.4%) cultures, and M. hominis in 17 (4.4%). Eight (2.1%) cultures were positive for both. Resistance of M. hominis to doxycycline, ciprofloxacin, ofloxacin, erytromycin, josamycin, pristinamycin and tetrascycline was 5.9%, 17.6%, 41.2%, 88.2%, 5.9%, 5.9% and 11.8%, respectively. Resistance to doxycycline, ciprofloxacin, ofloxacin, erytromycin, josamycin, pristinamycin and tetrascycline in U. urealyticum isolates was 1.6%, 40.5%, 58.4%, 54.0%, 1.6%, 8.1% and 13.5%, respectively. Both U. urealyticum (94.1%) and M. hominis (96.2) were most sensitive to josamycin, and most resistant to erytromycin (U. urealyticum 54.0%, M. hominis 88.2) and ofloxacin (U. urealyticum 58.4%, M. hominis 41.2%). As a result, the rate of U. urealyticum and M. hominis was found to be 48.4% and 4.4%, respectively. We conclude that doxycycline may be used in empirical treatment of genital tract infections in sexually active women.
المشرفين على المادة: 0 (Anti-Bacterial Agents)
تواريخ الأحداث: Date Created: 20060610 Date Completed: 20061019 Latest Revision: 20200923
رمز التحديث: 20231215
PMID: 16761537
قاعدة البيانات: MEDLINE