دورية أكاديمية

Analysis of the reactions used for the preparation of drug candidate molecules.

التفاصيل البيبلوغرافية
العنوان: Analysis of the reactions used for the preparation of drug candidate molecules.
المؤلفون: Carey JS; GlaxoSmithKline Pharmaceuticals, Old Powder Mills, Tonbridge, UK. john.s.carey@gsk.com, Laffan D, Thomson C, Williams MT
المصدر: Organic & biomolecular chemistry [Org Biomol Chem] 2006 Jun 21; Vol. 4 (12), pp. 2337-47. Date of Electronic Publication: 2006 May 03.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1477-0520 (Print) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Cambridge, UK : Royal Society of Chemistry, c2003-
مواضيع طبية MeSH: Pharmaceutical Preparations/*chemical synthesis, Chemistry, Pharmaceutical ; Drug Design ; Drug Industry/statistics & numerical data ; Pharmaceutical Preparations/chemistry
مستخلص: The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Process Chemistry R&D departments of GlaxoSmithKline, AstraZeneca and Pfizer.
Number of References: 24
المشرفين على المادة: 0 (Pharmaceutical Preparations)
تواريخ الأحداث: Date Created: 20060610 Date Completed: 20070717 Latest Revision: 20060609
رمز التحديث: 20240829
DOI: 10.1039/b602413k
PMID: 16763676
قاعدة البيانات: MEDLINE
الوصف
تدمد:1477-0520
DOI:10.1039/b602413k