دورية أكاديمية
Usefulness of rapid low-dose/high-dose 1-day 99mTc-sestamibi ECG-gated myocardial perfusion single-photon emission computed tomography.
| العنوان: | Usefulness of rapid low-dose/high-dose 1-day 99mTc-sestamibi ECG-gated myocardial perfusion single-photon emission computed tomography. |
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| المؤلفون: | Matsumoto N; Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan., Sato Y, Suzuki Y, Yoda S, Kunimasa T, Kato M, Tadehara F, Lewin HC, Hyun MC, Saito S |
| المصدر: | Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2006 Dec; Vol. 70 (12), pp. 1585-9. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Japanese Circulation Society Country of Publication: Japan NLM ID: 101137683 Publication Model: Print Cited Medium: Print ISSN: 1346-9843 (Print) Linking ISSN: 13469843 NLM ISO Abbreviation: Circ J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kyoto, Japan : Japanese Circulation Society, [2002- |
| مواضيع طبية MeSH: | Coronary Artery Disease/*diagnostic imaging , Heart/*diagnostic imaging , Technetium Tc 99m Sestamibi/*administration & dosage , Tomography, Emission-Computed, Single-Photon/*methods, Adult ; Aged ; Aged, 80 and over ; Coronary Circulation ; Electrocardiography ; Female ; Humans ; Male ; Middle Aged ; Time Factors |
| مستخلص: | Background: The clinical usefulness of a rapid rest low-dose/stress high-dose (dose ratio =1:5) (99m)Tc-sestamibi myocardial perfusion single-photon emission computed tomography (SPECT) protocol for the detection of coronary artery disease was evaluated. Methods and Results: In 89 patients, rest images were obtained immediately after the injection of (99m)Tc-sestamibi (256.1+/-28.4 MBq) followed by drinking water (400 ml). Exercise or vasodilator stress test was performed immediately after the completion of rest imaging with the injection of (99m)Tc-sestamibi (1312.3 +/-167.6 MBq). Prior to the post-stress imaging, patients were asked again to drink water (400 ml) in order to eliminate subdiaphragmatic tracer activity. The myocardial count ratio (stress/rest) of (99m)Tc-sestamibi was calculated. Image quality was scored using a 4-point scale system (4= excellent, 3= good, 2= poor, 1= unacceptable). Coronary angiography was performed in 56 patients within 1 month of the SPECT scan. All patients successfully performed the protocol and total examination time was 108+/-7 min. The myocardial count ratio of (99m)Tc-sestamibi was always greater than 6. The image quality was satisfactory both at rest (3.4+/-0.9) and after stress (3.9+/-0.2). The sensitivity and specificity to detect coronary artery stenosis >50% was 84% and 97%, respectively. Conclusions: This rapid one-day (99m)Tc-sestamibi protocol provides adequate image quality and diagnostic accuracy for detecting coronary artery disease. |
| المشرفين على المادة: | 971Z4W1S09 (Technetium Tc 99m Sestamibi) |
| تواريخ الأحداث: | Date Created: 20061128 Date Completed: 20070124 Latest Revision: 20190819 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1253/circj.70.1585 |
| PMID: | 17127804 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1346-9843 |
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| DOI: | 10.1253/circj.70.1585 |