دورية أكاديمية
[Genetic markers of pathogenicity of conditionally pathogenic enterobacteria isolated from children with diarrheal diseases].
| العنوان: | [Genetic markers of pathogenicity of conditionally pathogenic enterobacteria isolated from children with diarrheal diseases]. |
|---|---|
| المؤلفون: | Zherebtsova NIu, Baĭmiev AKh, Valishin DA, Mavziutov AR |
| المصدر: | Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2007 Mar-Apr (2), pp. 3-8. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Country of Publication: Russia (Federation) NLM ID: 0415217 Publication Model: Print Cited Medium: Print ISSN: 0372-9311 (Print) Linking ISSN: 03729311 NLM ISO Abbreviation: Zh Mikrobiol Epidemiol Immunobiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2018, no. 4 (ii︠u︡lʹ-avgust)- >: Moskva : FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Original Publication: Moskva : Izd-vo "Medit︠s︡ina" |
| مواضيع طبية MeSH: | Genes, Bacterial*, Enteritis/*microbiology , Enterobacteriaceae/*genetics , Enterobacteriaceae/*pathogenicity , Enterobacteriaceae Infections/*microbiology , Genomic Islands/*genetics, Acute Disease ; Adhesins, Bacterial/genetics ; Adolescent ; Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/genetics ; Bacterial Toxins/genetics ; Carrier Proteins ; Child ; Chloramphenicol/pharmacology ; Cytotoxins/genetics ; Diarrhea/microbiology ; Drug Resistance, Bacterial ; Enterobacteriaceae/classification ; Enterobacteriaceae/drug effects ; Escherichia coli Proteins/genetics ; Genetic Markers ; Hemolysin Proteins/genetics ; Humans ; Species Specificity ; Tetracycline/pharmacology ; Virulence Factors/genetics |
| مستخلص: | In the process of examination of 89 children from different age groups with diarrheal disease caused by bacteria from Enterobacteriaceae family 89 microorganisms were isolated including Klebsiella spp. (37 isolates), Citrobacter spp. (9 isolates), Enterobacter spp. (17 isolates), Hafnia alvei (1 isolate), Morganella morganii (11 isolates), Proteus spp. (14 isolates). Presence of genes associated with pathogenicity islands (PAIS): hlyA, hlyB (hemolysin), sfaG (fimbria antigen type S), cnf1 (cytotoxic necrotizing factor 1), estB (heat-stable enterotoxin B)were studied in these cultures by PCR. It was found that 32.6% of examined isolates had fragments of PAIS's genes--hlyA was detected in 9 cases (10.1%), hlyB--in 10 cases (11.2%), sfaG --in 8 cases (9%), cnf1--in 9 cases (10.1%), and estB--in 3 cases (3.4%). Positive correlation between genetic determinants hlyB and cnf1 as well as hlyA and sfaG was found while estB was not associated with other genes. Weak positive correlation between presence of sfaG and resistance to tetracycline and chloramphenicol was detected. Factors coded by revealed determinants of PAIS can play a role in the development of diarrheal syndrome. |
| المشرفين على المادة: | 0 (Adhesins, Bacterial) 0 (Anti-Bacterial Agents) 0 (Bacterial Proteins) 0 (Bacterial Toxins) 0 (Carrier Proteins) 0 (Cytotoxins) 0 (Escherichia coli Proteins) 0 (Genetic Markers) 0 (Hemolysin Proteins) 0 (Hlya protein, E coli) 0 (Hlyb protein, Bacteria) 0 (Virulence Factors) 106803-33-2 (cytotoxic necrotizing factor type 1) 66974FR9Q1 (Chloramphenicol) F8VB5M810T (Tetracycline) |
| تواريخ الأحداث: | Date Created: 20070526 Date Completed: 20070622 Latest Revision: 20200716 |
| رمز التحديث: | 20240628 |
| PMID: | 17523471 |
| قاعدة البيانات: | MEDLINE |
كن أول من يترك تعليقا!