دورية أكاديمية
Mucoid Pseudomonas in cystic fibrosis.
| العنوان: | Mucoid Pseudomonas in cystic fibrosis. |
|---|---|
| المؤلفون: | Pritt B; Clinical Microbiology, Mayo Clinic, Rochester, MN 55905, USA., O'Brien L, Winn W |
| المصدر: | American journal of clinical pathology [Am J Clin Pathol] 2007 Jul; Vol. 128 (1), pp. 32-4. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0370470 Publication Model: Print Cited Medium: Print ISSN: 0002-9173 (Print) Linking ISSN: 00029173 NLM ISO Abbreviation: Am J Clin Pathol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : Oxford : Oxford University Press Original Publication: Philadelphia [etc.] Lippincott [etc.] |
| مواضيع طبية MeSH: | Cystic Fibrosis/*microbiology , Pseudomonas aeruginosa/*isolation & purification, Alginates ; Glucuronic Acid/biosynthesis ; Hexuronic Acids ; Humans ; Pseudomonas aeruginosa/metabolism |
| مستخلص: | Pseudomonas aeruginosa is a frequent and virulent pulmonary pathogen in patients with cystic fibrosis. If colonization is not prevented, P aeruginosa becomes permanently established and nearly always mutates into a mucoid strain. The alginate-containing matrix of the mucoid strain is thought to allow the formation of protected microcolonies and provide increased resistance to opsonization, phagocytosis, and destruction by antibiotics. As a result, conversion to the mucoid phenotype is associated with a significant increase in morbidity and mortality. In the microbiology laboratory, mucoid P aeruginosa has a distinct Gram stain and culture appearance that can expedite its identification and facilitate appropriate patient management. Important aspects of the mucoid phenotype are reviewed. |
| المشرفين على المادة: | 0 (Alginates) 0 (Hexuronic Acids) 8A5D83Q4RW (Glucuronic Acid) |
| تواريخ الأحداث: | Date Created: 20070621 Date Completed: 20070726 Latest Revision: 20220317 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1309/KJRPC7DD5TR9NTDM |
| PMID: | 17580270 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0002-9173 |
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| DOI: | 10.1309/KJRPC7DD5TR9NTDM |