دورية أكاديمية

Large fetal sacrococcygeal teratomas: could early delivery improve outcome?

التفاصيل البيبلوغرافية
العنوان: Large fetal sacrococcygeal teratomas: could early delivery improve outcome?
المؤلفون: Holcroft CJ; Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA. cholcroft@jhmi.edu, Blakemore KJ, Gurewitsch ED, Driggers RW, Northington FJ, Fischer AC
المصدر: Fetal diagnosis and therapy [Fetal Diagn Ther] 2008; Vol. 24 (1), pp. 55-60. Date of Electronic Publication: 2008 May 27.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: S. Karger Country of Publication: Switzerland NLM ID: 9107463 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9964 (Electronic) Linking ISSN: 10153837 NLM ISO Abbreviation: Fetal Diagn Ther Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel ; New York : S. Karger, 1991-
مواضيع طبية MeSH: Gestational Age* , Sacrococcygeal Region*, Delivery, Obstetric/*mortality , Fetal Diseases/*mortality , Teratoma/*mortality, Female ; Humans ; Infant, Newborn ; Pregnancy ; Retrospective Studies ; Risk Assessment ; Teratoma/complications ; Teratoma/diagnostic imaging ; Ultrasonography, Prenatal
مستخلص: Objective: To determine if gestational age (GA) at delivery or tumor size impacts outcome in neonates with very large sacrococcygeal teratomas (SCTs).
Methods: Retrospective chart review from 1990 to 2006 of live-born infants with very large SCTs, defined as diameters exceeding 10 cm. Data analyzed using the independent t test and Fisher's exact test, with p values <0.05 considered significant.
Results: Nine infants with very large SCTs were identified. Six of the 9 infants survived, 4 of whom had evidence of early hydrops. Mean GA of survivors was 32.2 +/- 3.7 versus 31.7 +/- 0.6 weeks in nonsurvivors (p = 0.85). Infants with the largest SCTs did not survive.
Conclusion: Risks of preterm delivery must be weighed against complications from further enlargement of very large SCTs and against the risks of in utero intervention.
(Copyright 2008 S. Karger AG, Basel.)
تواريخ الأحداث: Date Created: 20080528 Date Completed: 20080918 Latest Revision: 20161124
رمز التحديث: 20240829
DOI: 10.1159/000132408
PMID: 18504383
قاعدة البيانات: MEDLINE
الوصف
تدمد:1421-9964
DOI:10.1159/000132408