دورية أكاديمية
Subgingival triclosan-polydimethylsiloxane gel as an adjunct to scaling and root planing.
| العنوان: | Subgingival triclosan-polydimethylsiloxane gel as an adjunct to scaling and root planing. |
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| المؤلفون: | Lecio G; Department of Periodontology, School of Dentistry, University of Florida, Gainesville, FL 32610, USA., Shaddox LM, Diniz Carvalho M, Duarte PM, Santos Tunes R, Nogueira-Filho GR, Sallum EA |
| المصدر: | American journal of dentistry [Am J Dent] 2008 Jun; Vol. 21 (3), pp. 171-4. |
| نوع المنشور: | Comparative Study; Journal Article; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mosher & Linder, Inc Country of Publication: United States NLM ID: 8806701 Publication Model: Print Cited Medium: Print ISSN: 0894-8275 (Print) Linking ISSN: 08948275 NLM ISO Abbreviation: Am J Dent |
| أسماء مطبوعة: | Original Publication: [San Antonio, TX : Mosher & Linder, Inc., c1988- |
| مواضيع طبية MeSH: | Dental Scaling* , Root Planing*, Anti-Infective Agents, Local/*therapeutic use , Dimethylpolysiloxanes/*therapeutic use , Periodontitis/*therapy , Triclosan/*therapeutic use, Administration, Topical ; Adult ; Anti-Infective Agents, Local/administration & dosage ; Combined Modality Therapy ; Dental Plaque Index ; Dimethylpolysiloxanes/administration & dosage ; Double-Blind Method ; Female ; Follow-Up Studies ; Gingival Hemorrhage/drug therapy ; Gingival Hemorrhage/therapy ; Gingival Recession/drug therapy ; Gingival Recession/therapy ; Humans ; Male ; Periodontal Attachment Loss/drug therapy ; Periodontal Attachment Loss/therapy ; Periodontal Pocket/drug therapy ; Periodontal Pocket/therapy ; Periodontitis/drug therapy ; Triclosan/administration & dosage |
| مستخلص: | Purpose: To evaluate the influence of a triclosan-polydimethylsiloxane-containing gel when used as an adjunct to scaling and root planing on the treatment of chronic periodontal disease. Methods: A 3-month, double-blind, randomized parallel design clinical trial was performed in 20 subjects with chronic periodontitis. The subjects, presenting at least three anterior sites with probing depth (PD) +/- 5 mm and bleeding on probing (BoP), were randomly assigned to two experimental groups: Group SRP-T: scaling/root planing plus test gel application (triclosan 1% + polydimethylsiloxane 13%) or Group SRP: scaling/root planing plus control gel application (polydimethylsiloxane 13%). Immediately following mechanical therapy, each assigned gel was applied to the selected sites and once a week during the following 3 weeks. Re-examinations were carried out on days 45 and 90 after the last irrigation. Results: Significant reductions in PD and clinical attachment level (CAL) were observed for both groups in both periods (P < 0.05). However, SRP-T showed lower means of PD than SRP at Day 45 (3.60 +/- 0.87 versus 4.77 +/- 1.38, respectively, P = 0.035) and CAL at both 45 days (4.63 +/- 1.17 versus 6.07 +/- 1.43, P = 0.023) and 90 days (4.45 +/- 1.19 versus 5.91 +/- 1.37, P = 0.021). No differences were found for bleeding on probing, plaque index and gingival recession (P > 0.05) between groups. |
| المشرفين على المادة: | 0 (Anti-Infective Agents, Local) 0 (Dimethylpolysiloxanes) 4NM5039Y5X (Triclosan) 63148-62-9 (baysilon) |
| تواريخ الأحداث: | Date Created: 20080809 Date Completed: 20081022 Latest Revision: 20131121 |
| رمز التحديث: | 20221213 |
| PMID: | 18686769 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0894-8275 |
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