دورية أكاديمية

[Optimization for formulation matrix proportion of xiangyu cataplasm by uniform design].

التفاصيل البيبلوغرافية
العنوان: [Optimization for formulation matrix proportion of xiangyu cataplasm by uniform design].
المؤلفون: Xu K; Wuhan University of Technology, Wuhan 430070, China. xuke_coco@163.com, Xu PH, Zhang XQ, Gao Y, Zhang L
المصدر: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials [Zhong Yao Cai] 2008 May; Vol. 31 (5), pp. 748-50.
نوع المنشور: English Abstract; Journal Article
اللغة: Chinese
بيانات الدورية: Publisher: Guo jia yi yao guan li ju Zhong yao cai qing bao zhong xin zhan Country of Publication: China NLM ID: 9426370 Publication Model: Print Cited Medium: Print ISSN: 1001-4454 (Print) Linking ISSN: 10014454 NLM ISO Abbreviation: Zhong Yao Cai Subsets: MEDLINE
أسماء مطبوعة: Publication: Guangzhou Shi : Guo jia yi yao guan li ju Zhong yao cai qing bao zhong xin zhan
Original Publication: Guangzhou Shi : Guo jia yi yao guan li ju Zhong yao cai qing bao zhong xin zhan,
مواضيع طبية MeSH: Drugs, Chinese Herbal/*chemistry , Gelatin/*chemistry , Plants, Medicinal/*chemistry, Adhesiveness ; Analysis of Variance ; Biocompatible Materials/chemistry ; Chemistry, Pharmaceutical ; Drug Combinations ; Drug Delivery Systems ; Drug Stability ; Drugs, Chinese Herbal/metabolism ; Skin Absorption ; Technology, Pharmaceutical/methods
مستخلص: Objective: To optimize the matrix formulation of cataplasm used to cure infantile diarrhea.
Methods: The optimum proportion of matrix for the preparation technology process of cataplasm was selected by uniform design and SPSS regression analysis. A check-up for adhibition , peeling strength, nonflowing, content of cream was founded.
Results: The best matrix's prescription gelatin: CMC-Na: PANA: kaolin: aluminum trichloride: citric acid: PVP K-30: PEG400: trimethylene glycol: tween-80 was 0.25 : 0.1 : 0.2 : 1.5 : 0.4 : 0.6 : 0.8 : 2 : 1 : 0.5.
Conclusion: The preparation technique of cataplasm is feasible, and its quality is steerable, it is a safe and effective transdermal-drug delivery system.
المشرفين على المادة: 0 (Biocompatible Materials)
0 (Drug Combinations)
0 (Drugs, Chinese Herbal)
9000-70-8 (Gelatin)
تواريخ الأحداث: Date Created: 20081002 Date Completed: 20091013 Latest Revision: 20081001
رمز التحديث: 20240829
PMID: 18826153
قاعدة البيانات: MEDLINE