دورية أكاديمية
[The use of ampicillin/sulbactam (Unasyn) in treating inflammatory urological diseases].
| العنوان: | [The use of ampicillin/sulbactam (Unasyn) in treating inflammatory urological diseases]. |
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| عنوان ترانسليتريتد: | Ispol'zovanie ampitsillin/sul'baktama (unazina) pri lechenii vospalitel'nykh urologicheskikh zabolevaniĭ. |
| المؤلفون: | Perepanova TS, Kotliarova GA, Kondrat'eva EM, Siniukhin VN, Derevianko II, Safin RN |
| المصدر: | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 1991 Jun; Vol. 36 (6), pp. 21-5. |
| نوع المنشور: | Comparative Study; English Abstract; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Izdatelstvo Meditsina Country of Publication: Russia (Federation) NLM ID: 8803688 Publication Model: Print Cited Medium: Print ISSN: 0235-2990 (Print) Linking ISSN: 02352990 NLM ISO Abbreviation: Antibiot Khimioter Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Moskva : Izdatelstvo Meditsina Original Publication: Moskva : Meditsina, c1988- |
| مواضيع طبية MeSH: | Ampicillin/*therapeutic use , Genital Diseases, Male/*drug therapy , Sulbactam/*therapeutic use , Urinary Tract Infections/*drug therapy, Adolescent ; Adult ; Aged ; Ampicillin/adverse effects ; Ampicillin/pharmacology ; Bacteria/drug effects ; Bacteria/isolation & purification ; Child ; Drug Evaluation ; Drug Therapy, Combination/adverse effects ; Drug Therapy, Combination/pharmacology ; Drug Therapy, Combination/therapeutic use ; Genital Diseases, Male/microbiology ; Humans ; Inflammation/drug therapy ; Inflammation/microbiology ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Sulbactam/adverse effects ; Sulbactam/pharmacology ; Urinary Tract Infections/microbiology |
| مستخلص: | Unasyn is a combination of ampicillin, a bactericidal antibiotic, and sulbactam, an inhibitor of beta-lactamases. It was used in treatment of 36 patients with urogenital infections. The combination was administered intravenously and in the main intramuscularly. The treatment course amounted to 7-10 days. The average daily dose was 6 to 9 g. 22 patients with acute nonocclusive pyelonephritis were treated with the combination and its clinical and bacteriological efficacy was stated in 95 per cent of the cases. An excellent clinical effect of the combination was observed in 6 patients with acute epididymitis. A clinical improvement was also observed in the treatment of the patients with acute prostatitis and chronic renal infections. Unasyn proved to be a highly efficient antibacterial combination with regard to gram-positive flora and colon bacilli as representatives of gram-negative organisms. Satisfactory results were also stated in the treatment of infections caused by Proteus spp. Complete elimination of the pathogen was achieved in 57.7 per cent of the cases. No adverse reactions to Unasyn except pain in the site of the injection were recorded. |
| المشرفين على المادة: | 65DT0ML581 (sultamicillin) 7C782967RD (Ampicillin) S4TF6I2330 (Sulbactam) |
| تواريخ الأحداث: | Date Created: 19910601 Date Completed: 19911024 Latest Revision: 20161020 |
| رمز التحديث: | 20231215 |
| PMID: | 1898184 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0235-2990 |
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