دورية أكاديمية
MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological differential diagnosis.
| العنوان: | MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological differential diagnosis. |
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| المؤلفون: | Roemer FW; Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA, USA. froemer@bu.edu, Frobell R, Hunter DJ, Crema MD, Fischer W, Bohndorf K, Guermazi A |
| المصدر: | Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2009 Sep; Vol. 17 (9), pp. 1115-31. Date of Electronic Publication: 2009 Mar 31. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: W.B. Saunders For The Osteoarthritis Research Society Country of Publication: England NLM ID: 9305697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9653 (Electronic) Linking ISSN: 10634584 NLM ISO Abbreviation: Osteoarthritis Cartilage Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : W.B. Saunders For The Osteoarthritis Research Society Original Publication: London : Published for the Society by Baillère Tindall, c1993- |
| مواضيع طبية MeSH: | Bone Marrow Diseases/*pathology , Knee Joint/*pathology , Magnetic Resonance Imaging/*methods, Bone Marrow/pathology ; Cartilage, Articular ; Diagnosis, Differential ; Humans ; Osteoarthritis, Knee/pathology |
| مستخلص: | Objective: To discuss terminology, radiological differential diagnoses and significance of magnetic resonance imaging (MRI)-detected subchondral bone marrow lesions (BMLs) of the knee joint. Methods: An overview of the published literature is presented. In addition, the radiological appearance and differential diagnosis of subchondral signal alterations of the knee joint are discussed based on expert consensus. A recommendation for terminology is provided and the relevance of these imaging findings for osteoarthritis (OA) research is emphasized. Results: A multitude of differential diagnoses of subchondral BMLs may present with a similar aspect and signal characteristics. For this reason it is crucial to clearly and specifically define the type of BML that is being assessed and to use terminology that is appropriate to the condition and the pathology. In light of the currently used terminology, supported by histology, it seems appropriate to apply the widely used term "bone marrow lesion" to the different entities of subchondral signal alterations and in addition to specifically and precisely define the analyzed type of BML. Water sensitive sequences such as fat suppressed T2-weighted, proton density-weighted, intermediate-weighted fast spin echo or short tau inversion recovery (STIR) sequences should be applied to assess non-cystic BMLs as only these sequences depict the lesions to their maximum extent. Assessment of subchondral non-cystic ill-defined BMLs on gradient echo-type sequences should be avoided as they will underestimate the size of the lesion. Differential diagnoses of OA related BMLs include traumatic bone contusions and fractures with or without disruption of the articular surface. Osteonecrosis and bone infarcts, inflammation, tumor, transient idiopathic bone marrow edema, red marrow and post-surgical alterations should also be considered. Conclusion: Different entities of subchondral BMLs that are of relevance in the context of OA research may be distinguished by specific imaging findings, patient characteristics, symptoms, and history and are discussed in this review. |
| Number of References: | 82 |
| تواريخ الأحداث: | Date Created: 20090411 Date Completed: 20100416 Latest Revision: 20220409 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1016/j.joca.2009.03.012 |
| PMID: | 19358902 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1522-9653 |
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| DOI: | 10.1016/j.joca.2009.03.012 |