دورية أكاديمية
[Analysis of distribution, drug resistance and risk factors of pathogens isolated from septicemic patients].
| العنوان: | [Analysis of distribution, drug resistance and risk factors of pathogens isolated from septicemic patients]. |
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| المؤلفون: | Sun L; Department of Epidemiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. deland@fimmu.com, Nie J, Rui YY, Wang Q, Qiu YR, Geng SN |
| المصدر: | Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2009 May; Vol. 29 (5), pp. 990-2. |
| نوع المنشور: | Journal Article |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Nanfang yi ke da xue xue bao bian ji bu Country of Publication: China NLM ID: 101266132 Publication Model: Print Cited Medium: Print ISSN: 1673-4254 (Print) Linking ISSN: 16734254 NLM ISO Abbreviation: Nan Fang Yi Ke Da Xue Xue Bao Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Guangzhou : Nanfang yi ke da xue xue bao bian ji bu, 2005- |
| مواضيع طبية MeSH: | Drug Resistance, Bacterial*, Gram-Negative Bacteria/*isolation & purification , Sepsis/*microbiology, Adolescent ; Adult ; Aged ; Candida albicans/drug effects ; Candida albicans/isolation & purification ; Child ; Child, Preschool ; Escherichia coli/drug effects ; Escherichia coli/isolation & purification ; Female ; Gram-Negative Bacteria/drug effects ; Humans ; Infant ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/isolation & purification ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/isolation & purification ; Risk Factors ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/isolation & purification ; Young Adult |
| مستخلص: | Objective: To investigate distribution, drug resistance and risk factors of pathogens isolated from septicemic patients in a hospital in the past 6 years. Methods: Most of the bacterial isolates were identified with BD Phoenix, and a few isolates were identified manually and with K-B method. Candida isolates were identified with color display plates and K-B method. WHONET5.4 software was used for analysis. Results: The common bacteria isolated form the blood included E. coli, P. aeruginosa, K. pneumoniae, and S. aureu. The gram-negative bacillus from the blood exhibited relatively low resistance to such antibiotics as cefoperazone/sulbactam, imipenem, amikacin, piperacillin/tazobactam, and ceftazidime, and the incidences of E.coli and K. pneumoniae isolates producing extended spectrum beta-lactamase (ESBLs) ranged between 33.3% and 34.9% and between 32.9% and 36.0%, respectively. The gram-positive coccus from blood showed a sensitivity rate of 100.0% to vancomycin and low resistant rates to amikacin and chloramphenicol; the methicillin-resistant rates of S. aureu and coagulase-negative staphylococcus were 26.9%-35.5% and 72.7%-74.3%, respectively. The risk factors of septicemia included hospital stay for over 5 days, venous catheterization, surgeries, puncture, oxygen therapy, urine tract catheterization, and chemotherapy. Conclusion: Blood culture can be of importance in patients with septicemia, and the use of antibiotics should be carefully weighed according to the results of bacterial culture and sensitivity tests of the pathogens isolated from the blood. |
| تواريخ الأحداث: | Date Created: 20090523 Date Completed: 20100504 Latest Revision: 20201209 |
| رمز التحديث: | 20240829 |
| PMID: | 19460728 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1673-4254 |
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