دورية أكاديمية
Descemet membrane endothelial keratoplasty with a stromal rim (DMEK-S).
| العنوان: | Descemet membrane endothelial keratoplasty with a stromal rim (DMEK-S). |
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| المؤلفون: | Studeny P; Department of Ophthalmology, Sokolov Hospital, Sokolov, Czech Republic. studenypavel@seznam.cz, Farkas A, Vokrojova M, Liskova P, Jirsova K |
| المصدر: | The British journal of ophthalmology [Br J Ophthalmol] 2010 Jul; Vol. 94 (7), pp. 909-14. Date of Electronic Publication: 2009 Oct 22. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 0421041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2079 (Electronic) Linking ISSN: 00071161 NLM ISO Abbreviation: Br J Ophthalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 1992- : London : BMJ Pub. Group Original Publication: 1917-Dec. 1991: London : British Medical Association |
| مواضيع طبية MeSH: | Corneal Diseases/*surgery , Corneal Stroma/*transplantation , Descemet Stripping Endothelial Keratoplasty/*methods, Aged ; Aged, 80 and over ; Female ; Follow-Up Studies ; Fuchs' Endothelial Dystrophy/surgery ; Graft Rejection ; Humans ; Male ; Middle Aged ; Reoperation ; Retrospective Studies ; Tissue and Organ Harvesting/methods ; Treatment Outcome ; Visual Acuity |
| مستخلص: | Aim: To describe a novel technique for the preparation and transplantation of posterior corneal lamellae consisting of endothelium and bare Descemet membrane with a stromal supporting rim. Methods: Posterior lamellar discs for Descemet membrane endothelial keratoplasty with a stromal rim (DMEK-S) were prepared manually immediately before surgery using the big bubble technique. The retrospective case series that underwent DMEK-S comprised 20 eyes of 18 patients with endothelial dysfunction. Best-corrected visual acuity (BCVA) and endothelial cell density (ECD) were measured preoperatively and 12-24 months after DMEK-S. Results: At the end of the follow-up, 10 out of 18 eyes achieved a BCVA of 1.0 or better, and 17 reached 0.5 or better. Primary graft failure occurred in two eyes. The average ECD at 1 year was 1608 (+/-503) cells/mm(2), that is, a mean cell loss from preoperative values of 44%. Partial early postoperative graft detachment (12 of 20 eyes) was treated by injecting an air bubble into the anterior chamber in all cases. The loss of donor corneas during preparation decreased from approximately 10 to 5% as more experience was acquired with the procedure. Conclusions: Preliminary outcomes show that DMEK-S may be used in the treatment of corneal endothelial dysfunction. As this approach is entirely manual, and no special surgical equipment is needed, it has the potential to become widely adopted. |
| تواريخ الأحداث: | Date Created: 20091024 Date Completed: 20100729 Latest Revision: 20100707 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1136/bjo.2009.165134 |
| PMID: | 19850580 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1468-2079 |
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| DOI: | 10.1136/bjo.2009.165134 |