دورية أكاديمية
Delayed intraocular pressure elevation after pupillary dilation in exfoliation syndrome.
| العنوان: | Delayed intraocular pressure elevation after pupillary dilation in exfoliation syndrome. |
|---|---|
| المؤلفون: | Shihadeh WA; Einhorn Clinical Research Centre, New York Eye and Ear Infirmary, New York City, NY 10003, USA. wisam97@yahoo.com, Ritch R, Scharf B, Liebmann JM |
| المصدر: | Acta ophthalmologica [Acta Ophthalmol] 2011 Sep; Vol. 89 (6), pp. 560-2. Date of Electronic Publication: 2009 Oct 30. |
| نوع المنشور: | Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101468102 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-3768 (Electronic) Linking ISSN: 1755375X NLM ISO Abbreviation: Acta Ophthalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford, UK : Wiley-Blackwell Original Publication: Oxford, UK ; Malden, MA : Blackwell Munksgaard |
| مواضيع طبية MeSH: | Exfoliation Syndrome/*diagnosis , Intraocular Pressure/*physiology , Mydriatics/*administration & dosage , Ocular Hypertension/*diagnosis , Pupil/*drug effects, Aged ; Drug Combinations ; Exfoliation Syndrome/physiopathology ; Female ; Gonioscopy ; Humans ; Male ; Middle Aged ; Ocular Hypertension/physiopathology ; Phenylephrine/administration & dosage ; Prospective Studies ; Time Factors ; Tonometry, Ocular ; Tropicamide/administration & dosage |
| مستخلص: | Purpose: To determine the effect of pupillary dilation on intraocular pressure (IOP) in normotensive patients with exfoliation syndrome (XFS). Methods: Patients with XFS were enrolled in this prospective trial. All eyes were untreated, had no previous laser or operative surgery and were normotensive with full visual fields and open angles. IOP was measured before dilation and hourly for four consecutive hours after dilation with tropicamide 1% and phenylephrine 2.5% eyedrops. Results: Twenty-five eyes of 19 White patients (nine male, 10 female) with XFS were enrolled. Twelve eyes (48%) had a rise in IOP of ≥ 4 mmHg above the pre-dilation baseline IOP and four (16%) had a rise of ≥ 9 mmHg (9-28 mmHg). Post-dilation gonioscopy confirmed the presence of an open anterior chamber angle in all eyes. The maximum IOP was reached 3 hr post-dilation in three eyes and after 2 hr in the remaining eyes. The four eyes with marked IOP rise exhibited an elevation of between 1 and 7 mmHg at 1 hr. Extensive pigment release was noticed in all eyes that had a rise in IOP. Conclusion: Patients with XFS are at risk of developing delayed post-dilation IOP rises. Awareness of this phenomenon is particularly important in patients with advanced cupping and/or severe visual field loss who may not be able to tolerate a marked elevation of IOP. An early, mild rise in IOP at 1 hr may serve as a warning sign for a more severe, delayed response. Eyes with XFS should be monitored carefully after dilation, especially those with marked pigment release. (© 2009 The Authors. Journal compilation © 2009 Acta Ophthalmol.) |
| المشرفين على المادة: | 0 (Drug Combinations) 0 (Mydriatics) 1WS297W6MV (Phenylephrine) N0A3Z5XTC6 (Tropicamide) |
| تواريخ الأحداث: | Date Created: 20091103 Date Completed: 20111212 Latest Revision: 20131121 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1111/j.1755-3768.2009.01744.x |
| PMID: | 19878115 |
| قاعدة البيانات: | MEDLINE |
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