دورية أكاديمية
Efficacy of prophylactic antibiotics for dental implants: a multicentre placebo-controlled randomised clinical trial.
| العنوان: | Efficacy of prophylactic antibiotics for dental implants: a multicentre placebo-controlled randomised clinical trial. |
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| المؤلفون: | Esposito M; Oral and Maxillofacial Surgery, School of Denstistry, The University of Manchester, Manchester, UK. espositomarco@hotmail.com, Cannizzaro G, Bozzoli P, Consolo U, Felice P, Ferri V, Landriani S, Leone M, Magliano A, Pellitteri G, Todisco M, Torchio C |
| المصدر: | European journal of oral implantology [Eur J Oral Implantol] 2008 Spring; Vol. 1 (1), pp. 23-31. |
| نوع المنشور: | Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Quintessence Pub Country of Publication: England NLM ID: 101473719 Publication Model: Print Cited Medium: Print ISSN: 1756-2406 (Print) Linking ISSN: 17562406 NLM ISO Abbreviation: Eur J Oral Implantol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Surrey : Quintessence Pub. |
| مواضيع طبية MeSH: | Antibiotic Prophylaxis* , Dental Implants*, Amoxicillin/*therapeutic use, Adolescent ; Adult ; Aged ; Dental Abutments ; Dental Restoration Failure ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Osseointegration/physiology ; Placebos ; Postoperative Complications ; Surgical Wound Dehiscence/etiology ; Surgical Wound Infection/etiology ; Treatment Outcome ; Young Adult |
| مستخلص: | Purpose: To evaluate the efficacy of prophylactic antibiotics for dental implant placement. Materials and Methods: Twelve Italian private practices agreed to participate in this trial, each centre providing 30 patients. One hour prior to implant placement, patients were randomised, for consumption orally of 2 g amoxicillin or identical placebo tablets. Patients needing bone augmentation procedures were not included. Outcome measures were prosthesis and implant failures, adverse events and post-operative biological complications. Patients were seen 1 week, 2 weeks and 4 months post-operatively. Results: One centre did not deliver any data and 14 patients had to be excluded from the trial for various reasons. One hundred and fifty-eight patients were evaluated in each group and none dropped out at 4 months. Two prostheses and two implants failed in the antibiotics group, compared with four prostheses and nine implants in the placebo group. There were no statistically significant differences for prosthesis failures, implant losses, complications and side effects. Conclusions: No statistically significant differences were observed. However, four times more patients in the placebo group experienced implant failures than in the antibiotic group, and this requires further investigation. |
| المشرفين على المادة: | 0 (Dental Implants) 0 (Placebos) 804826J2HU (Amoxicillin) |
| تواريخ الأحداث: | Date Created: 20100515 Date Completed: 20100610 Latest Revision: 20220317 |
| رمز التحديث: | 20221213 |
| PMID: | 20467641 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1756-2406 |
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