دورية أكاديمية
Routine evaluation and treatment of unexplained menorrhagia: do we consider haemostatic disorders?
| العنوان: | Routine evaluation and treatment of unexplained menorrhagia: do we consider haemostatic disorders? |
|---|---|
| المؤلفون: | Knol HM; Division of Haemostasis and Thrombosis, Department of Haematology, University Medical Centre Groningen, Groningen, The Netherlands. h.m.knol@og.umcg.nl, Bogchelman DH, Kluin-Nelemans HC, van der Zee AG, van der Meer J, Meijer K |
| المصدر: | European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 2010 Oct; Vol. 152 (2), pp. 191-4. Date of Electronic Publication: 2010 Jun 25. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 0375672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7654 (Electronic) Linking ISSN: 03012115 NLM ISO Abbreviation: Eur J Obstet Gynecol Reprod Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Limerick : Elsevier Scientific Publishers Original Publication: Amsterdam, Excerpta Medica. |
| مواضيع طبية MeSH: | Hemostatic Disorders/*complications , Menorrhagia/*etiology, Adolescent ; Adult ; Anemia/etiology ; Endometrial Ablation Techniques ; Female ; Humans ; Menorrhagia/surgery ; Menorrhagia/therapy ; Middle Aged ; Patient Satisfaction ; Retrospective Studies |
| مستخلص: | Objective: Unexplained menorrhagia can be caused by underlying bleeding disorders. The aim of this study was to investigate the current work-up of menorrhagia in routine gynaecological practice, with a special interest in haemostatic evaluation. Secondly, we investigated the outcome of individualized treatment in our centre. Study Design: Retrospective medical chart review of 112 consecutive patients referred with menorrhagia to a general gynaecology clinic of a university teaching hospital in the Netherlands between January 2006 and January 2007. In April 2008 we performed a structured telephone interview evaluating the effectiveness of their therapy. Results: We included 112 patients, whose median age was 42 years. Twenty-nine percent were anaemic (hemoglobin <12.0g/dL). Seventy-one (63%) had unexplained menorrhagia. Only two patients had haemostatic evaluation and neither had von Willebrand's disease. Forty percent (29/71) needed two or more different therapies, 17% (12/71) needed three different therapies and two patients needed a total of seven different therapies. Eight patients underwent hysterectomy, six of them after endometrial ablation. Most patients (80%) were successfully treated medically or surgically and were satisfied with their therapy during follow-up. Eleven patients declined therapy and accepted their heavy periods. Conclusion: Haemostatic evaluation in women with unexplained menorrhagia is uncommon in gynaecological practice in our centre. Although most of the patients were satisfied with their treatment, a significant number required hysterectomy and another important proportion had to accept their menorrhagia. We hypothesize that the identification of haemostatic disorders might improve care for these women. (Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.) |
| تواريخ الأحداث: | Date Created: 20100626 Date Completed: 20110211 Latest Revision: 20101011 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.ejogrb.2010.05.026 |
| PMID: | 20576344 |
| قاعدة البيانات: | MEDLINE |
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