دورية أكاديمية
أعرض في EDS

Patterns of non-traumatic myelopathies in Yaounde (Cameroon): a hospital based study.

التفاصيل البيبلوغرافية
العنوان: Patterns of non-traumatic myelopathies in Yaounde (Cameroon): a hospital based study.
المؤلفون: Lekoubou Looti AZ; Faculty of Medicine and Biomedical Sciences, Yaounde I, Hôpital Neurologique, 59 Bd Pinel, Lyon 69500, France. lekoub77@yahoo.com, Kengne AP, Djientcheu Vde P, Kuate CT, Njamnshi AK
المصدر: Journal of neurology, neurosurgery, and psychiatry [J Neurol Neurosurg Psychiatry] 2010 Jul; Vol. 81 (7), pp. 768-70.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 2985191R Publication Model: Print Cited Medium: Internet ISSN: 1468-330X (Electronic) Linking ISSN: 00223050 NLM ISO Abbreviation: J Neurol Neurosurg Psychiatry Subsets: MEDLINE
أسماء مطبوعة: Publication: London : BMJ Publishing Group
Original Publication: London : British Medical Association
مواضيع طبية MeSH: Spinal Cord Diseases/*pathology, Adult ; Anal Canal/pathology ; Cameroon/epidemiology ; Female ; Hospitals ; Humans ; Infections/complications ; Infections/epidemiology ; Liver Neoplasms/complications ; Liver Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Metastasis ; Paraplegia/etiology ; Paraplegia/pathology ; Quadriplegia/etiology ; Quadriplegia/pathology ; Sensation ; Sex Factors ; Spinal Cord Compression/complications ; Spinal Cord Compression/pathology ; Spinal Cord Diseases/complications ; Spinal Cord Diseases/epidemiology
مستخلص: Background: The relative frequency of compressive and non-compressive myelopathies and their aetiologies have not been evaluated extensively in most sub-Saharan African countries. The case of Cameroon is studied.
Methods: Admission registers and case records of patients in the neurology and neurosurgery departments of the study hospital were reviewed from January 1999 to December 2006.
Results: 224 (9.7% of all admissions) cases were non-traumatic paraplegia/paraparesis or tetraplegia/tetraparesis and 147 were due to myelopathies, representing 6.3% of all cases admitted during the study period and 65.6% of cases of paraplegia or tetraplegia; 88% were compressive myelopathies. Aetiologies were dominated by primary and secondary spinal tumours (mainly prostate carcinoma, lymphoma and liver carcinoma) that each accounted for 24.5% of cases. Other causes included spinal tuberculosis (12.9%), tropical spastic paraparesis (five positive for human T cell lymphotrophic virus (HTLV)-I and one for HTLV-II) (4.8%), spinal degenerative disease (4.1%), acute transverse myelitis (4.1%), HIV myelopathy (1.4%), vitamin B12 deficiency myelopathy and multiple sclerosis (0.7%). No aetiology was found in 21.1% of participants.
Conclusions: Myelopathies in our setting are dominated by spinal compressions. Metastasis is a leading cause of spinal cord compression with liver carcinoma being more frequent than reported elsewhere. Infections nevertheless remain a major cause of spinal cord disease and both cancers and infections constitute public health targets for reducing the incidence of myelopathies.
تواريخ الأحداث: Date Created: 20100629 Date Completed: 20100709 Latest Revision: 20220330
رمز التحديث: 20231215
DOI: 10.1136/jnnp.2009.177519
PMID: 20581141
قاعدة البيانات: MEDLINE
الوصف
تدمد:1468-330X
DOI:10.1136/jnnp.2009.177519