دورية أكاديمية
Deposition of trans fatty acid from industrial sources and its effect on different growth phases in rats.
| العنوان: | Deposition of trans fatty acid from industrial sources and its effect on different growth phases in rats. |
|---|---|
| المؤلفون: | Lessa NM; Department of Nutrition and Health, Federal University of Viçosa, Brazil., Nakajima VM, Matta SL, Peluzio MC, Sabarense CM, Costa NM |
| المصدر: | Annals of nutrition & metabolism [Ann Nutr Metab] 2010; Vol. 57 (1), pp. 23-34. Date of Electronic Publication: 2010 Jul 27. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Karger Country of Publication: Switzerland NLM ID: 8105511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9697 (Electronic) Linking ISSN: 02506807 NLM ISO Abbreviation: Ann Nutr Metab Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel ; New York : Karger, [1981- |
| مواضيع طبية MeSH: | Animal Nutritional Physiological Phenomena*, Dietary Fats/*pharmacology , Insulin Resistance/*physiology , Trans Fatty Acids/*pharmacology, Adipose Tissue/metabolism ; Adipose Tissue/pathology ; Animals ; Female ; Insulin/blood ; Insulin/pharmacology ; Lipid Metabolism ; Liver/metabolism ; Liver/physiology ; Male ; Rats ; Rats, Wistar |
| مستخلص: | Although the effects of trans fatty acids (TFA) from industrially produced sources (IP-TFA), such as partially hydrogenated vegetable oil, are reported, their implications on metabolism and growth are still not fully disclosed. In this study, female Wistar rats were assigned to control diet (AIN-93G) or Trans diet groups (5% IP-TFA) after gestation. The male offspring were classified and grouped as infant, weanling, and young adult (YA) rats (n = 10), and received the same control or Trans diets throughout their life span. Samples of abdominal adipose tissue, liver and plasma were collected to determine fatty acid profile and fasting glycemia. Morphometric analysis of the liver and hepatosomatic index determination were conducted. Deposition of TFA was observed in the liver, adipose tissue and plasma of IP-TFA-fed rats. Fasting glycemia concentration was higher in Trans YA rats than in the control YA group (p = 0.004). A higher accumulation of fat was observed in the liver of the Trans group than in the control group during the three phases. Hepatosomatic index was higher in the YA Trans group than in the YA control group (p < 0.05). Dietary TFA was deposited in the tissues and plasma and raised fasting glucose in growing rats. (2010 S. Karger AG, Basel.) |
| المشرفين على المادة: | 0 (Dietary Fats) 0 (Insulin) 0 (Trans Fatty Acids) |
| تواريخ الأحداث: | Date Created: 20100729 Date Completed: 20101124 Latest Revision: 20111117 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1159/000314080 |
| PMID: | 20664255 |
| قاعدة البيانات: | MEDLINE |
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