دورية أكاديمية
Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients.
| العنوان: | Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients. |
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| المؤلفون: | Patel AR; Department of Orthopaedic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Crist MK, Nemitz J, Mayerson JL |
| المصدر: | Journal of surgical oncology [J Surg Oncol] 2010 Sep 01; Vol. 102 (3), pp. 276-81. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0222643 Publication Model: Print Cited Medium: Internet ISSN: 1096-9098 (Electronic) Linking ISSN: 00224790 NLM ISO Abbreviation: J Surg Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2005-> : Hoboken, NJ : Wiley-Liss Original Publication: New York, Plenum. |
| مواضيع طبية MeSH: | Intermittent Pneumatic Compression Devices*, Aspirin/*therapeutic use , Bone Neoplasms/*surgery , Heparin/*therapeutic use , Heparin, Low-Molecular-Weight/*therapeutic use , Orthopedic Procedures/*adverse effects , Sarcoma/*surgery , Venous Thromboembolism/*prevention & control, Adult ; Aged ; Bone Neoplasms/secondary ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies |
| مستخلص: | Background: Deep venous thrombosis (DVT) and pulmonary embolism (PE) are possible sources of morbidity and mortality in patients with musculoskeletal neoplasms (MSN). Objective: To compare the efficacy of aspirin (ASA) and pneumatic compression devices (PCD) to low-molecular-weight heparin (LMWH) and PCD in patients undergoing orthopedic procedures for MSN of the pelvis or lower extremity. Methods: Of 348 patients who met the study criteria, 195 were treated with ASA/PCD and 153 with LMWH/PCD. There were 18 DVT including 8 in ASA/PCD group and 10 in LMWH/PCD group. There were four PEs, all in the LMWH/PCD group. Results: We found no significant difference in DVT rate between ASA/PCD and LMWH/PCD when used for prophylaxis against thromboembolic complications. Our analysis shows that procedures of the thigh, soft tissue resections, and malignant disease were more often managed with ASA/PCD while joint arthroplasty, procedures of the hip/pelvis, and metastatic disease were more often managed with LMWH/PCD. Conclusion: DVT prophylaxis in orthopedic oncology remains a complex topic in which physicians must balance the risks of thromboembolic disease against the risks of post-operative complications. (2010 Wiley-Liss, Inc.) |
| المشرفين على المادة: | 0 (Heparin, Low-Molecular-Weight) 9005-49-6 (Heparin) R16CO5Y76E (Aspirin) |
| تواريخ الأحداث: | Date Created: 20100827 Date Completed: 20100915 Latest Revision: 20131121 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1002/jso.21603 |
| PMID: | 20740587 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1096-9098 |
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| DOI: | 10.1002/jso.21603 |