دورية أكاديمية
أعرض في EDS

Diagnosis and management of iron deficiency anemia in patients with IBD.

التفاصيل البيبلوغرافية
العنوان: Diagnosis and management of iron deficiency anemia in patients with IBD.
المؤلفون: Stein J; Gastroenterology and Clinical Nutrition, St Elisabeth Hospital, Katharina Kasper Clinics, Teaching Hospital of the Goethe University Frankfurt, Ginnheimer Street 3, D-60487 Frankfurt, Germany. j.stein@em.uni-frankfurt.de, Hartmann F, Dignass AU
المصدر: Nature reviews. Gastroenterology & hepatology [Nat Rev Gastroenterol Hepatol] 2010 Nov; Vol. 7 (11), pp. 599-610. Date of Electronic Publication: 2010 Oct 05.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500079 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-5053 (Electronic) Linking ISSN: 17595045 NLM ISO Abbreviation: Nat Rev Gastroenterol Hepatol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London ; New York : Nature Pub. Group, c2009-
مواضيع طبية MeSH: Anemia, Iron-Deficiency*/diagnosis , Anemia, Iron-Deficiency*/drug therapy , Anemia, Iron-Deficiency*/epidemiology, Inflammatory Bowel Diseases/*epidemiology , Iron/*therapeutic use, Humans ; Prevalence
مستخلص: Anemia is the most prevalent extraintestinal complication of IBD. It can affect quality of life and ability to work, and can also increase the hospitalization rate in patients with IBD. Although the causes of anemia in IBD are multifactorial, iron deficiency anemia (IDA) is the most common. Assessment of the iron status of patients who have a condition associated with inflammation, such as IBD, by using common biochemical values is insufficient. However, new indices of iron metabolism (for instance ferritin:transferrin receptor ratio, reticulocyte hemoglobin content or percentage of hypochromic red blood cells) may help to improve the assessment of iron status in patients with IBD. The treatment of IDA traditionally involves oral iron supplementation. However, because of extensive gastrointestinal adverse effects, and data showing that the use of oral iron in IBD may be associated with disease exacerbation, current guidelines suggest that iron supplementation in IBD should be administered intravenously. This Review provides an overview of iron homeostasis in health before discussing diagnostic and therapeutic strategies for IDA in patients with IBD.
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المشرفين على المادة: E1UOL152H7 (Iron)
تواريخ الأحداث: Date Created: 20101007 Date Completed: 20110217 Latest Revision: 20220408
رمز التحديث: 20221213
DOI: 10.1038/nrgastro.2010.151
PMID: 20924367
قاعدة البيانات: MEDLINE
الوصف
تدمد:1759-5053
DOI:10.1038/nrgastro.2010.151