دورية أكاديمية

[A 32P application device for the treatment of condyloma acuminatum in the rectum].

التفاصيل البيبلوغرافية
العنوان: [A 32P application device for the treatment of condyloma acuminatum in the rectum].
المؤلفون: Ma YB; Department of Nuclear Medicine, The Ninth People's Hospital, China. myb7802@126.com, Liu YW, Gu AC, Xu F, Liu PA, Yuan SF, Zhai CT
المصدر: Zhonghua nan ke xue = National journal of andrology [Zhonghua Nan Ke Xue] 2011 Jan; Vol. 17 (1), pp. 47-51.
نوع المنشور: Comparative Study; English Abstract; Journal Article; Randomized Controlled Trial
اللغة: Chinese
بيانات الدورية: Publisher: Nanjing Jun Qu Nanjing Zong Yi Yuan zhu ban, Zhonghua Nan Ke Xue Za Zhi Bian Ji Bu bian ji chu ban Country of Publication: China NLM ID: 101093592 Publication Model: Print Cited Medium: Print ISSN: 1009-3591 (Print) Linking ISSN: 10093591 NLM ISO Abbreviation: Zhonghua Nan Ke Xue Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Nanjing : Nanjing Jun Qu Nanjing Zong Yi Yuan zhu ban, Zhonghua Nan Ke Xue Za Zhi Bian Ji Bu bian ji chu ban,
مواضيع طبية MeSH: Condylomata Acuminata/*therapy , Drug Delivery Systems/*instrumentation , Phosphorus Radioisotopes/*therapeutic use , Rectal Diseases/*therapy, Adult ; Female ; Humans ; Male ; Microwaves/therapeutic use ; Middle Aged ; Phosphorus Radioisotopes/administration & dosage ; Rectal Diseases/virology ; Young Adult
مستخلص: Objective: To investigate the use of a 32P application device (AD) in the treatment of condyloma acuminatum (CA) in the rectum, and to compare its clinical effect with that of the microwave therapy.
Methods: This study included 107 cases of CA in the rectum, 99 males and 8 females, aged 21-58 (33.6 +/- 9.4) years. Forty-six of the patients (the AD group) were treated with a self-made 32P application device, which, as a tube-shaped carrier of radionuclide 32P colloid, was fixed in the rectum at the diseased part for medication at 4.9-8.2 Gy for 3-5 hours once and 1-2 times a week. The other 61 (the microwave group) were treated by microwave burning under local anesthesia. Both groups of patients were followed up for over 3 months for comparison of the therapeutic results and observation of the stability and reliability of the 32P application device.
Results: The rates of cure, reoccurrence and adverse reaction were 84, 8%, 13.0% and 8.7% in the AD group, compared with 40.3%, 55.7% and 75.4% in the microwave group, with statistically significant differences between the two groups (P < 0.01).
Conclusion: The 32P application device, with its advantages of low cost, easy operation, good effect, high safety and reliability, low recurrence, fewer adverse events and good acceptability, is highly valuable for the treatment of CA in the rectum.
المشرفين على المادة: 0 (Phosphorus Radioisotopes)
تواريخ الأحداث: Date Created: 20110301 Date Completed: 20111115 Latest Revision: 20110225
رمز التحديث: 20221213
PMID: 21351532
قاعدة البيانات: MEDLINE