دورية أكاديمية
[Plasma catecholamines in consciousness recovery in patients with severe traumatic brain injury].
العنوان: | [Plasma catecholamines in consciousness recovery in patients with severe traumatic brain injury]. |
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المؤلفون: | Aleksandrova EV, Zaĭtsev OS, Tenedieva VD, Potapov AA, Zakharova NE, Kravchuk AD, Oshorov AV, Sokolova EIu, Shukhraĭ VA, Vorob'ev IuV |
المصدر: | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2011; Vol. 111 (3), pp. 58-63. |
نوع المنشور: | English Abstract; Journal Article |
اللغة: | Russian |
بيانات الدورية: | Publisher: Media Sfera Country of Publication: Russia (Federation) NLM ID: 9712194 Publication Model: Print Cited Medium: Print ISSN: 1997-7298 (Print) Linking ISSN: 19977298 NLM ISO Abbreviation: Zh Nevrol Psikhiatr Im S S Korsakova Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <1995->: Moskva : Media Sfera Original Publication: Moskva : "Meditsina", |
مواضيع طبية MeSH: | Consciousness*, Brain Injuries/*blood , Brain Injuries/*therapy , Catecholamines/*blood , Unconsciousness/*blood , Unconsciousness/*therapy, Adolescent ; Adult ; Child ; Dopamine/blood ; Female ; Glasgow Coma Scale ; Humans ; Male ; Middle Aged ; Norepinephrine/blood ; Young Adult |
مستخلص: | Changes in plasma noradrenalin (NA) and dopamine (DA) levels were evaluated in the stages of consciousness recovery in patients with severe traumatic brain injury with and without deep brain structure damage. Forty-eight patients (36 men and 12 women), aged from 12 to 56 (31,9±10,9) yeas, were enrolled in the study. Two variants of catecholamine (CA) changes were found: 1) a CA-dissociation that was oppositely directed to NA and DA changes was observed in unconsciousness; 2) a CA-dissociation (unidirectional NA and DA changes) that was observed after the restoration of consciousness. In patients with the damage of two frontal lobes and deep brain structures, CA-association periods were seen in the stage of mental confusion with psychomotor agitation or when the brain stem was damaged. The duration of CA-association was negatively correlated with the velocity, quality of consciousness recovery and outcomes evaluated by the Glasgow scale. |
المشرفين على المادة: | 0 (Catecholamines) VTD58H1Z2X (Dopamine) X4W3ENH1CV (Norepinephrine) |
تواريخ الأحداث: | Date Created: 20110323 Date Completed: 20110602 Latest Revision: 20161018 |
رمز التحديث: | 20221213 |
PMID: | 21423117 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1997-7298 |
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