دورية أكاديمية
أعرض في EDS

Heart failure survival score in patients with Chagas disease: correlation with functional variables.

التفاصيل البيبلوغرافية
العنوان: Heart failure survival score in patients with Chagas disease: correlation with functional variables.
المؤلفون: Ritt LE; Departamento de Cardiologia, Universidade Federal de São Paulo, São Paulo, Brazil., Carvalho AC, Feitosa GS, Pinho-Filho JA, Macedo CR, Vilas-Boas F, Andrade MV, Feitosa-Filho GS, Almeida AJ, Barojas M, Lopes RD
المصدر: Revista espanola de cardiologia (English ed.) [Rev Esp Cardiol (Engl Ed)] 2012 Jun; Vol. 65 (6), pp. 538-43. Date of Electronic Publication: 2012 Apr 16.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Doyma Country of Publication: Spain NLM ID: 101587954 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1885-5857 (Electronic) Linking ISSN: 18855857 NLM ISO Abbreviation: Rev Esp Cardiol (Engl Ed) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Barcelona : Elsevier Doyma
مواضيع طبية MeSH: Chagas Cardiomyopathy/*mortality , Heart Failure/*mortality , Ventricular Dysfunction, Left/*mortality, Adrenergic beta-Antagonists/therapeutic use ; Adult ; Aged ; Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Chagas Cardiomyopathy/complications ; Chagas Cardiomyopathy/physiopathology ; Echocardiography ; Exercise Test/methods ; Female ; Heart Failure/drug therapy ; Heart Failure/etiology ; Heart Failure/physiopathology ; Humans ; Male ; Middle Aged ; Quality of Life ; Survival Analysis ; Ventricular Dysfunction, Left/drug therapy ; Ventricular Dysfunction, Left/etiology ; Ventricular Dysfunction, Left/physiopathology ; Young Adult
مستخلص: Introduction and Objectives: Chagas disease is a prevalent cause of heart failure in Latin America, and its prognosis is worse than other etiologies. The Heart Failure Survival Score has been used to assess prognosis in patients with heart failure; however, this score has not yet been studied in patients with Chagas cardiopathy.
Methods: The Heart Failure Survival Score was calculated in 55 patients with severe left ventricular systolic dysfunction due to Chagas disease. Correlations were assessed between the Heart Failure Survival Score and variables obtained from, cardiopulmonary exercise tests, quality-of-life measures, and 6-minute walking tests.
Results: Patients were distributed among New York Heart Association classes II-IV; 89% were taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, 62% were taking beta-blockers, 86% were taking diuretics, and 74% were taking aldosterone receptor blockers. The mean Heart Failure Survival Score was 8.75 (0.80). The score correlated well with cardiopulmonary test variables such as peak oxygen uptake (0.662; P<.01), oxygen uptake at the anaerobic threshold (0.644; P<.01), ventilation carbon dioxide efficiency slope (-0.417; P<.01), oxygen pulse (0.375; P<.01), oxygen uptake efficiency slope (0.626; P<.01), 6-minute walking test (0.370; P<.01), left ventricle ejection fraction (0.650; P=.01), and left atrium diameter (-0.377; P<.01). There was also a borderline significant correlation between the Heart Failure Survival Score and quality of life (-0.283; P<.05).
Conclusions: In heart failure patients with Chagas disease, the Heart Failure Survival Score correlated well with the main prognostic functional test variables.
(Copyright © 2011 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved.)
المشرفين على المادة: 0 (Adrenergic beta-Antagonists)
0 (Angiotensin Receptor Antagonists)
0 (Angiotensin-Converting Enzyme Inhibitors)
تواريخ الأحداث: Date Created: 20120420 Date Completed: 20120921 Latest Revision: 20121231
رمز التحديث: 20221213
DOI: 10.1016/j.recesp.2011.12.019
PMID: 22513344
قاعدة البيانات: MEDLINE
الوصف
تدمد:1885-5857
DOI:10.1016/j.recesp.2011.12.019