دورية أكاديمية
[Effects of recombinant mechano-dependent growth factor against the background of chronic alcoholisation in rats].
العنوان: | [Effects of recombinant mechano-dependent growth factor against the background of chronic alcoholisation in rats]. |
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المؤلفون: | Lysenko EA, Turtikova OV, Morozkina EV, Khotchenkov VP, Popov VO, Shenkman BS |
المصدر: | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2012 Feb; Vol. 98 (2), pp. 283-92. |
نوع المنشور: | English Abstract; Journal Article |
اللغة: | Russian |
بيانات الدورية: | Publisher: Nauka Country of Publication: Russia (Federation) NLM ID: 9715665 Publication Model: Print Cited Medium: Print ISSN: 0869-8139 (Print) Linking ISSN: 08698139 NLM ISO Abbreviation: Ross Fiziol Zh Im I M Sechenova Subsets: MEDLINE |
أسماء مطبوعة: | Publication: S.-Peterburg : Nauka Original Publication: Sankt-Peterburg : "Nauka", c1997- |
مواضيع طبية MeSH: | Alcoholism/*metabolism , Cell Proliferation/*drug effects , Insulin-Like Growth Factor I/*administration & dosage , Muscle, Skeletal/*metabolism, Alcoholism/pathology ; Animals ; Cadherins/metabolism ; Cell Nucleolus/drug effects ; Gene Expression Regulation/drug effects ; Male ; Muscle, Skeletal/cytology ; Paired Box Transcription Factors/metabolism ; Phosphorylation/drug effects ; Rats ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; Ribosomal Protein S6 Kinases, 90-kDa/metabolism |
مستخلص: | In alcoholised rats, proliferation of satellite cells consistently decreased as well as the number of myonuclei, while phosphorylation of p90RSK became reduced. The mechano-growth factor abministration increased the proliferate activity of the myogenic precursors and restored the myonuclei pool. Phosphorylation of p90RSK increased too. |
المشرفين على المادة: | 0 (Cadherins) 0 (PAX7 protein, rat) 0 (Paired Box Transcription Factors) 0 (mechano-growth factor, rat) 142845-03-2 (M-cadherin) 67763-96-6 (Insulin-Like Growth Factor I) EC 2.7.11.1 (Ribosomal Protein S6 Kinases, 70-kDa) EC 2.7.11.1 (Ribosomal Protein S6 Kinases, 90-kDa) |
تواريخ الأحداث: | Date Created: 20120602 Date Completed: 20120731 Latest Revision: 20161020 |
رمز التحديث: | 20221213 |
PMID: | 22650072 |
قاعدة البيانات: | MEDLINE |
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