دورية أكاديمية
Self-reported dietary intake of potassium, calcium, and magnesium and risk of dementia in the Japanese: the Hisayama Study.
العنوان: | Self-reported dietary intake of potassium, calcium, and magnesium and risk of dementia in the Japanese: the Hisayama Study. |
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المؤلفون: | Ozawa M; Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Ninomiya T, Ohara T, Hirakawa Y, Doi Y, Hata J, Uchida K, Shirota T, Kitazono T, Kiyohara Y |
المصدر: | Journal of the American Geriatrics Society [J Am Geriatr Soc] 2012 Aug; Vol. 60 (8), pp. 1515-20. Date of Electronic Publication: 2012 Aug 02. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Blackwell Science Country of Publication: United States NLM ID: 7503062 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-5415 (Electronic) Linking ISSN: 00028614 NLM ISO Abbreviation: J Am Geriatr Soc Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Malden, MA : Blackwell Science Original Publication: New York [etc.] |
مواضيع طبية MeSH: | Diet* , Self Report*, Calcium, Dietary/*administration & dosage , Dementia/*epidemiology , Magnesium/*administration & dosage , Potassium, Dietary/*administration & dosage, Aged ; Asian People ; Cohort Studies ; Dementia/prevention & control ; Female ; Humans ; Japan/epidemiology ; Male ; Prospective Studies ; Risk |
مستخلص: | Objectives: To investigate whether higher intake of potassium, calcium, and magnesium reduces the risk of incident dementia. Design: Prospective cohort study. Setting: The Hisayama Study, in Japan. Participants: One thousand eighty-one community-dwelling Japanese individuals without dementia aged 60 and older. Measurements: A 70-item semiquantitative food frequency questionnaire was used to assess potassium, calcium, and magnesium intakes. Hazard ratios (HRs) for the development of all-cause dementia and its subtypes were estimated using Cox proportional hazards model. Results: During a 17-year follow-up, 303 participants experienced all-cause dementia; of these, 98 had vascular dementia (VaD), and 166 had Alzheimer's disease (AD). The multivariable-adjusted HRs for the development of all-cause dementia were 0.52 (95% confidence interval [CI] = 0.30-0.91), 0.64 (95% CI = 0.41-1.00), and 0.63 (95% CI = 0.40-1.01) for the highest quartiles of potassium, calcium, and magnesium intake, respectively, compared with the corresponding lowest quartiles. Similarly, the HRs for the development of VaD were 0.20 (95% CI = 0.07-0.56), 0.24 (95% CI = 0.11-0.53), and 0.26 (95% CI = 0.11-0.61) for the highest quartiles of potassium, calcium, and magnesium intake, respectively. There was no evidence of a linear association between these mineral intakes and the risk of AD. Conclusion: Higher self-reported dietary intakes of potassium, calcium, and magnesium reduce the risk of all-cause dementia, especially VaD, in the general Japanese population. (© 2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society.) |
التعليقات: | Comment in: Evid Based Ment Health. 2013 Feb;16(1):26. (PMID: 23154787) |
المشرفين على المادة: | 0 (Calcium, Dietary) 0 (Potassium, Dietary) I38ZP9992A (Magnesium) |
تواريخ الأحداث: | Date Created: 20120807 Date Completed: 20121024 Latest Revision: 20221207 |
رمز التحديث: | 20221213 |
DOI: | 10.1111/j.1532-5415.2012.04061.x |
PMID: | 22860881 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1532-5415 |
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DOI: | 10.1111/j.1532-5415.2012.04061.x |