دورية أكاديمية

Clinical Inquiry. Do inhaled steroids reduce bone mineral density and increase fracture risk?

التفاصيل البيبلوغرافية
العنوان: Clinical Inquiry. Do inhaled steroids reduce bone mineral density and increase fracture risk?
المؤلفون: Wheelock C; Family Medicine of Southwest Washington, Vancouver, USA., Glass J, St Anna L
المصدر: The Journal of family practice [J Fam Pract] 2012 Aug; Vol. 61 (8), pp. 493-508.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Frontline Medical Communications Country of Publication: United States NLM ID: 7502590 Publication Model: Print Cited Medium: Internet ISSN: 1533-7294 (Electronic) Linking ISSN: 00943509 NLM ISO Abbreviation: J Fam Pract Subsets: MEDLINE
أسماء مطبوعة: Publication: Parsippany, NJ : Frontline Medical Communications
Original Publication: New York, Appleton-Century-Crofts.
مواضيع طبية MeSH: Adrenal Cortex Hormones/*adverse effects , Asthma/*drug therapy , Bone Density/*drug effects , Fractures, Spontaneous/*etiology , Pulmonary Disease, Chronic Obstructive/*drug therapy, Administration, Inhalation ; Adrenal Cortex Hormones/administration & dosage ; Adult ; Aged ; Aged, 80 and over ; Asthma/diagnosis ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Evidence-Based Medicine ; Female ; Fractures, Spontaneous/epidemiology ; Humans ; Incidence ; Male ; Middle Aged ; Patient Safety ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Randomized Controlled Trials as Topic ; Risk Assessment
مستخلص: No, except perhaps at high doses. Inhaled corticosteroids at low to medium doses (<1500 mcg beclomethasone hydrofluoroalkane per day) for asthma and chronic obstructive pulmonary disease don't increase the risk of significant bone loss or fracture at 2 to 3 years follow-up. Higher doses, however, may raise the risk of nontraumatic fracture over 1 to 4 years of follow-up.
المشرفين على المادة: 0 (Adrenal Cortex Hormones)
تواريخ الأحداث: Date Created: 20120809 Date Completed: 20130110 Latest Revision: 20120808
رمز التحديث: 20231215
PMID: 22871660
قاعدة البيانات: MEDLINE