دورية أكاديمية
[Comprehensive analysis on variation of cardiac enzyme and troponin induced by acute organophosphorous poisoning].
| العنوان: | [Comprehensive analysis on variation of cardiac enzyme and troponin induced by acute organophosphorous poisoning]. |
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| المؤلفون: | Wan WG; Department of Occupational diseases, Huashan Hosipital, Fudan University, Shanghai 200040, China., Jiang L, Zheng SC, Qiu HM, Xuan DD, Zou HJ |
| المصدر: | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases [Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi] 2012 Jun; Vol. 30 (6), pp. 452-5. |
| نوع المنشور: | English Abstract; Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Tianjin shi lao dong wei sheng yan jiu suo ; Tianjin shi lao dong wei sheng huan jing yi xue hui Country of Publication: China NLM ID: 8410840 Publication Model: Print Cited Medium: Print ISSN: 1001-9391 (Print) Linking ISSN: 10019391 NLM ISO Abbreviation: Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Tientsin] : Tianjin shi lao dong wei sheng yan jiu suo ; Tianjin shi lao dong wei sheng huan jing yi xue hui, [1983- |
| مواضيع طبية MeSH: | Cardiomyopathies/*diagnosis , Myocardium/*metabolism , Organophosphate Poisoning/*metabolism, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cardiomyopathies/etiology ; Child ; Child, Preschool ; Creatine Kinase/blood ; Creatine Kinase, MB Form/blood ; Female ; Humans ; Infant ; Male ; Middle Aged ; Myocardium/enzymology ; Myocardium/pathology ; Troponin I/blood ; Troponin T/blood ; Young Adult |
| مستخلص: | Objective: To discuss the diagnostic value of cardiac enzyme and troponin in acute organophosphorus pesticide poisoning (AOPP). Methods: A retrospective study was performed in the document published in domestic journals and PubMed from 1979 to 2010. The data of the cardiac enzyme and troponin were collected. Statistical analysis was conducted with one-way ANOVA and rank sum test. 2129 cases with AOPP were enrolled. Results: The levels of creatine kinase (CK), creatine kinase-MB (CK-MB) and cardiac troponin I (cTnI) in milder, moderate and severe poisoning groups were significantly elevated compared by the healthy control group (P < 0.05). The differences were also dramatic among three patients groups (P < 0.05). The ratios of CK-MB to CK in both moderate and severe groups were significantly lower than in healthy controls (P < 0.05). The levels of CK, CK-MB and cTnI were higher especially in patients with intermediate myasthenic syndrome (IMS) than patients without IMS. Meanwhile, the levels of CK and CK-MB were elevated in patients with respiratory failure compared by non-failure ones, but decreased in the ratios of CK-MB to CK (P < 0.05). Conclusions: The elevation of CK and CK-MB in serum could not be judged as the criteria of myocardial damage in AOPP, the ratio of CK-MB to CK were more valuable; the value of cTnI in myocardial damage was still in suspect. CK, CK-MB and cTnI could be used as auxiliary criteria of AOPP classification. |
| المشرفين على المادة: | 0 (Troponin I) 0 (Troponin T) EC 2.7.3.2 (Creatine Kinase) EC 2.7.3.2 (Creatine Kinase, MB Form) |
| تواريخ الأحداث: | Date Created: 20120831 Date Completed: 20130918 Latest Revision: 20120830 |
| رمز التحديث: | 20231215 |
| PMID: | 22931775 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1001-9391 |
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