دورية أكاديمية
Prevalence and pattern of brown adipose tissue distribution of 18F-FDG in patients undergoing PET-CT in a subtropical climatic zone.
| العنوان: | Prevalence and pattern of brown adipose tissue distribution of 18F-FDG in patients undergoing PET-CT in a subtropical climatic zone. |
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| المؤلفون: | Perkins AC; Radiological and Imaging Sciences, Medical Physics, Medical School Queen’s Medical Centre, University of Nottingham, Nottingham, NG7 2UH, UK. alan.perkins@nottingham.ac.uk, Mshelia DS, Symonds ME, Sathekge M |
| المصدر: | Nuclear medicine communications [Nucl Med Commun] 2013 Feb; Vol. 34 (2), pp. 168-74. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 8201017 Publication Model: Print Cited Medium: Internet ISSN: 1473-5628 (Electronic) Linking ISSN: 01433636 NLM ISO Abbreviation: Nucl Med Commun Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Lippincott Williams & Wilkins Original Publication: London : Chapman and Hall in association with the British Nuclear Medicine Society, c1980- |
| مواضيع طبية MeSH: | Fluorodeoxyglucose F18*/metabolism , Multimodal Imaging* , Positron-Emission Tomography* , Tomography, X-Ray Computed* , Tropical Climate*, Adipose Tissue, Brown/*diagnostic imaging , Adipose Tissue, Brown/*metabolism, Adolescent ; Adult ; Biological Transport ; Child ; Child, Preschool ; Ethnicity/statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Organ Specificity ; Prevalence ; Seasons ; Young Adult |
| مستخلص: | Background: The uptake of F-FDG in brown adipose tissue (BAT) may have important implications in understanding the pathophysiology of BAT and obesity. Because of the thermal implications of BAT uptake of F-FDG, this study aimed to contribute to existing knowledge by assessing patients scanned in a subtropical environment with particular reference to ethnicity. Patients and Methods: A retrospective study was carried out to determine the prevalence and pattern of BAT uptake in patients undergoing F-FDG PET-CT imaging in a PET facility located in a subtropical climatic zone. Standardized uptake values were obtained for regions of BAT uptake of F-FDG, and the distribution pattern was assessed according to anatomical region, sex, age, BMI and ethnicity. Results: Following a reveiw of a total of 386 scans, 38 patients showed BAT uptake of F-FDG (9.85%), with the mass and activity of BAT being greater in women than in men (11.95 and 6.88%, respectively). BAT uptake of F-FDG in the neck/supraclavicular, axillary and mediastinal regions was greater in adults whose BMI was less than 18 kg/m. However, perirenal BAT activity was shown to be greater in obese individuals. The frequency of BAT uptake of F-FDG was 55% in winter as against 45% during summer (P<0.012). There was no statistical difference in BAT uptake between black and white patients. Conclusion: This study shows the pattern and prevalence of BAT in patients in a subtropical environment. Although the average seasonal temperatures are higher in a subtropical climate, a seasonal variation in BAT expression was observed, although there were no differences with respect to patient ethnicity. |
| المشرفين على المادة: | 0Z5B2CJX4D (Fluorodeoxyglucose F18) |
| تواريخ الأحداث: | Date Created: 20121201 Date Completed: 20130723 Latest Revision: 20211203 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1097/MNM.0b013e32835bbbf0 |
| PMID: | 23196673 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1473-5628 |
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| DOI: | 10.1097/MNM.0b013e32835bbbf0 |