دورية أكاديمية
Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis.
| العنوان: | Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. |
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| المؤلفون: | Vahabnezhad E; Departments of Pediatrics Gastroenterology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. evahabnezhad@mednet.ucla.edu, Mochon AB, Wozniak LJ, Ziring DA |
| المصدر: | Journal of clinical gastroenterology [J Clin Gastroenterol] 2013 May-Jun; Vol. 47 (5), pp. 437-9. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 7910017 Publication Model: Print Cited Medium: Internet ISSN: 1539-2031 (Electronic) Linking ISSN: 01920790 NLM ISO Abbreviation: J Clin Gastroenterol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2015- > : Philadelphia, PA : Wolters Kluwer Health, Inc. Original Publication: New York, Masson. |
| مواضيع طبية MeSH: | Lacticaseibacillus rhamnosus*/classification , Lacticaseibacillus rhamnosus*/genetics , Lacticaseibacillus rhamnosus*/isolation & purification , Lacticaseibacillus rhamnosus*/pathogenicity, Bacteremia/*microbiology , Colitis, Ulcerative/*therapy , Probiotics/*adverse effects , Probiotics/*therapeutic use, Anti-Bacterial Agents/therapeutic use ; Bacteremia/drug therapy ; Gram-Positive Bacterial Infections/drug therapy ; Gram-Positive Bacterial Infections/microbiology ; Humans ; Immunocompromised Host ; Male ; RNA, Ribosomal, 16S/genetics ; Risk Factors ; Sequence Analysis, DNA |
| مستخلص: | Probiotic strains of Lactobacillus are currently used in a variety of clinical practices with limited evidence to support their use. Lactobacillus species are a normal part of gastrointestinal flora, and bacteremia with probiotic strains of Lactobacillus is very uncommon. We describe a case of Lactobacillus bacteremia in a 17-year-old boy with ulcerative colitis managed with systemic corticosteroids and infliximab, who presented with fever to 102°F, flushing, and chills 1 week after starting Lactobacillus rhamnosus GG probiotics. Initial blood culture on day 2 of his fever was positive for Lactobacillus, however, subsequent blood cultures on day 3 and 5 were negative. He was treated empirically with antibiotics for 5 days and defervesced by day 8 of his illness. 16 S rRNA sequence analysis identified the organism from the patient's blood culture and probiotic capsule as L. rhamnosus with a 99.78% match for both the strains. This case report highlights the potential risk of Lactobacillus bacteremia in immunosuppressed patients with severe active ulcerative colitis. |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) 0 (RNA, Ribosomal, 16S) |
| تواريخ الأحداث: | Date Created: 20130222 Date Completed: 20131017 Latest Revision: 20221207 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1097/MCG.0b013e318279abf0 |
| PMID: | 23426446 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1539-2031 |
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| DOI: | 10.1097/MCG.0b013e318279abf0 |