دورية أكاديمية
Activity of succinate dehydrogenase in the neocortex and hippocampus of Mongolian gerbils with ischemic and reperfusion brain injury.
| العنوان: | Activity of succinate dehydrogenase in the neocortex and hippocampus of Mongolian gerbils with ischemic and reperfusion brain injury. |
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| المؤلفون: | Shcherbak NS; I. P. Pavlov St. Petersburg State Medical University, St. Petersburg, Russia. ShcherbakNS@yandex.ru, Galagudza MM, Ovchinnikov DA, Kuzmenkov AN, Yukina GY, Barantsevich ER, Tomson VV, Shlyakhto EV |
| المصدر: | Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2013 May; Vol. 155 (1), pp. 14-7. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: United States NLM ID: 0372557 Publication Model: Print Cited Medium: Internet ISSN: 1573-8221 (Electronic) Linking ISSN: 00074888 NLM ISO Abbreviation: Bull Exp Biol Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York : Springer Original Publication: New York, Consultants Bureau. |
| مواضيع طبية MeSH: | Brain Ischemia/*enzymology , Hippocampus/*enzymology , Neocortex/*enzymology , Pyramidal Cells/*enzymology , Reperfusion Injury/*enzymology , Succinate Dehydrogenase/*metabolism, Animals ; Brain/metabolism ; Brain Injuries/enzymology ; Gerbillinae ; Male |
| مستخلص: | We analyzed changes in activity of SDH, one of the most important enzymes of the Krebs cycle, in the cytoplasm of hippocampal and cortical neurons of Mongolian gerbils (Meriones unguiculatus) at the early and delayed reperfusion period after global brain ischemia. The data indicate that SDH activity in pyramidal neurons of various hippocampal areas and in neurons of II, III and V layers of cerebral cortex after 7-min forebrain ischemia depends on both the localization of these neurons and duration of the postischemic reperfusion. SDH activity in neurons significantly increased on days 2 and 7 after reperfusion. |
| المشرفين على المادة: | EC 1.3.99.1 (Succinate Dehydrogenase) |
| تواريخ الأحداث: | Date Created: 20130514 Date Completed: 20140221 Latest Revision: 20190813 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1007/s10517-013-2068-6 |
| PMID: | 23667861 |
| قاعدة البيانات: | MEDLINE |
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