دورية أكاديمية
And then there were none: no need for pluripotency factors to induce reprogramming.
| العنوان: | And then there were none: no need for pluripotency factors to induce reprogramming. |
|---|---|
| المؤلفون: | Chou BK; Stem Cell Program in the Institute for Cell Engineering and Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Cheng L |
| المصدر: | Cell stem cell [Cell Stem Cell] 2013 Sep 05; Vol. 13 (3), pp. 261-2. |
| نوع المنشور: | Journal Article; Comment |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Cambridge, MA : Cell Press |
| مواضيع طبية MeSH: | Cell Dedifferentiation*, Cell Engineering/*methods , Cellular Reprogramming/*drug effects , Fibroblasts/*drug effects , Fibroblasts/*physiology , GATA3 Transcription Factor/*metabolism , Induced Pluripotent Stem Cells/*cytology , Induced Pluripotent Stem Cells/*metabolism , Octamer Transcription Factor-3/*metabolism , Pluripotent Stem Cells/*physiology , Small Molecule Libraries/*pharmacology , Transcription Factors/*metabolism, Animals ; Humans |
| مستخلص: | While most factors used as reprogramming transgenes can be replaced by other means, Oct4 has remained essential until now. Three recent papers have now broken this barrier through the use of opposing lineage specifying transgenes and chemical modulation, thus signifying a milestone in advancing our understanding of pluripotency induction. (Copyright © 2013 Elsevier Inc. All rights reserved.) |
| التعليقات: | Comment on: Cell. 2013 May 23;153(5):963-75. (PMID: 23706735) Comment on: Science. 2013 Aug 9;341(6146):651-4. (PMID: 23868920) Comment on: Cell Stem Cell. 2013 Sep 5;13(3):341-50. (PMID: 23871606) |
| References: | Cell. 1992 Sep 4;70(5):841-7. (PMID: 1381289) Cell Stem Cell. 2011 Apr 8;8(4):363-9. (PMID: 21474100) Cell. 2013 May 23;153(5):963-75. (PMID: 23706735) Science. 2013 Aug 9;341(6146):651-4. (PMID: 23868920) Nature. 1992 Oct 8;359(6395):550-1. (PMID: 1383830) Cell Stem Cell. 2013 Sep 5;13(3):341-50. (PMID: 23871606) Cell. 2011 Jun 10;145(6):875-89. (PMID: 21663792) Cell Stem Cell. 2012 Apr 6;10(4):440-54. (PMID: 22482508) Cell. 2006 Aug 25;126(4):663-76. (PMID: 16904174) |
| معلومات مُعتمدة: | P30 CA006973 United States CA NCI NIH HHS |
| المشرفين على المادة: | 0 (GATA3 Transcription Factor) 0 (GATA3 protein, human) 0 (Octamer Transcription Factor-3) 0 (POU5F1 protein, human) 0 (Small Molecule Libraries) 0 (Transcription Factors) |
| تواريخ الأحداث: | Date Created: 20130910 Date Completed: 20140408 Latest Revision: 20211021 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC4659384 |
| DOI: | 10.1016/j.stem.2013.08.004 |
| PMID: | 24012365 |
| قاعدة البيانات: | MEDLINE |
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