دورية أكاديمية
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Is your system calibrated? MRI gradient system calibration for pre-clinical, high-resolution imaging.

التفاصيل البيبلوغرافية
العنوان: Is your system calibrated? MRI gradient system calibration for pre-clinical, high-resolution imaging.
المؤلفون: O'Callaghan J; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom., Wells J; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom., Richardson S; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom; UCL Centre for Medical Image Computing, London, United Kingdom., Holmes H; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom., Yu Y; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom., Walker-Samuel S; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom., Siow B; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom; UCL Centre for Medical Image Computing, London, United Kingdom., Lythgoe MF; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom.
المصدر: PloS one [PLoS One] 2014 May 07; Vol. 9 (5), pp. e96568. Date of Electronic Publication: 2014 May 07 (Print Publication: 2014).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Phantoms, Imaging*, Magnetic Resonance Imaging/*instrumentation, Calibration
مستخلص: High-field, pre-clinical MRI systems are widely used to characterise tissue structure and volume in small animals, using high resolution imaging. Both applications rely heavily on the consistent, accurate calibration of imaging gradients, yet such calibrations are typically only performed during maintenance sessions by equipment manufacturers, and potentially with acceptance limits that are inadequate for phenotyping. To overcome this difficulty, we present a protocol for gradient calibration quality assurance testing, based on a 3D-printed, open source, structural phantom that can be customised to the dimensions of individual scanners and RF coils. In trials on a 9.4 T system, the gradient scaling errors were reduced by an order of magnitude, and displacements of greater than 100 µm, caused by gradient non-linearity, were corrected using a post-processing technique. The step-by-step protocol can be integrated into routine pre-clinical MRI quality assurance to measure and correct for these errors. We suggest that this type of quality assurance is essential for robust pre-clinical MRI experiments that rely on accurate imaging gradients, including small animal phenotyping and diffusion MR.
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معلومات مُعتمدة: 16463 United Kingdom CRUK_ Cancer Research UK; NC/K500276/1 United Kingdom NC3RS_ National Centre for the Replacement, Refinement and Reduction of Animals in Research; United Kingdom WT_ Wellcome Trust; 100247 United Kingdom WT_ Wellcome Trust; MR/J013110/1 United Kingdom MRC_ Medical Research Council
تواريخ الأحداث: Date Created: 20140509 Date Completed: 20151007 Latest Revision: 20240210
رمز التحديث: 20240210
مُعرف محوري في PubMed: PMC4013024
DOI: 10.1371/journal.pone.0096568
PMID: 24804737
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0096568