دورية أكاديمية
Magnetic resonance imaging-guided occult breast lesion localization and simultaneous sentinel lymph node mapping.
| العنوان: | Magnetic resonance imaging-guided occult breast lesion localization and simultaneous sentinel lymph node mapping. |
|---|---|
| المؤلفون: | de Lima Docema MF, Costa PA, de Andrade FE, Bevilacqua JL, Elias S; Discipline of Mastology, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Rua Botucatu 740, Vila Clementino, CEP 04023-062, São Paulo, SP, Brazil. simone.elias3@gmail.com., Cerri GG, Barros AC, Nazario AC |
| المصدر: | World journal of surgical oncology [World J Surg Oncol] 2014 Oct 23; Vol. 12, pp. 320. Date of Electronic Publication: 2014 Oct 23. |
| نوع المنشور: | Evaluation Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819 (Electronic) Linking ISSN: 14777819 NLM ISO Abbreviation: World J Surg Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BioMed Central, 2003- |
| مواضيع طبية MeSH: | Lymph Nodes*/pathology , Lymph Nodes*/surgery, Breast Neoplasms/*diagnosis , Carcinoma, Ductal, Breast/*diagnosis , Carcinoma, Intraductal, Noninfiltrating/*diagnosis , Carcinoma, Lobular/*diagnosis , Magnetic Resonance Imaging/*methods , Preoperative Care/*methods, Adult ; Aged ; Axilla ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Ductal, Breast/surgery ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Carcinoma, Intraductal, Noninfiltrating/surgery ; Carcinoma, Lobular/pathology ; Carcinoma, Lobular/surgery ; Contrast Media ; Feasibility Studies ; Female ; Humans ; Lymph Node Excision ; Lymphatic Metastasis ; Middle Aged ; Organometallic Compounds |
| مستخلص: | Background: Radio-guided occult lesion localization is a valid technique for the diagnosis of suspicious non-palpable lesions. Here we determine the feasibility of pre-operative localization of occult suspect non-palpable breast lesions using radio-guided occult lesion localization, as well as for identifying the sentinel lymph node. Methods: This is a descriptive study of data collected retrospectively. Pre-operative mapping of 34 breast lesions in 25 patients suspected of being malignant was performed using conventional imaging methods with a magnetic resonance imaging-guided radiopharmaceutical injection. Results: The mean time required to perform the localization was 25 minutes. After resection of the lesions using a gamma probe, malignancy was confirmed in fifteen patients (60.0%), with nine invasive ductal carcinomas, two invasive lobular carcinomas, and four in situ ductal carcinomas The resection was confirmed by the complete removal of the radioactive material. The pathologic results and images were concordant in all but two cases, which were submitted for new magnetic resonance imaging examinations and surgery that confirmed the malignancies. Of the 15 patients with confirmed malignancies, 10 had sentinel lymph node resection. Of these, eight were negative for metastases, one had micro-metastases and one had confirmed metastases. Three patients had full axillary node dissection, with metastases found in only one. No side effects were observed with magnetic resonance-guided radiopharmaceutical injection. Conclusions: The sentinel node occult lesion localization technique is a simple, reproducible and effective alternative approach to occult lesions compared to other methods, such as mammotomy and the hook-wire localization technique, for mapping suspect breast lesions and identifying lymph node metastasis. |
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| المشرفين على المادة: | 0 (Contrast Media) 0 (Organometallic Compounds) RLM74T3Z9D (gadoversetamide) |
| تواريخ الأحداث: | Date Created: 20141025 Date Completed: 20150701 Latest Revision: 20191210 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC4219021 |
| DOI: | 10.1186/1477-7819-12-320 |
| PMID: | 25341393 |
| قاعدة البيانات: | MEDLINE |
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