دورية أكاديمية
أعرض في EDS

Use of short-term circulatory support as a bridge in pediatric heart transplantation.

التفاصيل البيبلوغرافية
العنوان: Use of short-term circulatory support as a bridge in pediatric heart transplantation.
المؤلفون: Canêo LF; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Miana LA; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Tanamati C; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Penha JG; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Shimoda MS; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Azeka E; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Miura N; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Galas FR; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Guimarães VA; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Jatene MB; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
المصدر: Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2015 Jan; Vol. 104 (1), pp. 78-84. Date of Electronic Publication: 2014 Nov 04.
نوع المنشور: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
اللغة: English; Portuguese
بيانات الدورية: Publisher: Sociedad Brasileira De Cardiologia Country of Publication: Brazil NLM ID: 0421031 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4170 (Electronic) Linking ISSN: 0066782X NLM ISO Abbreviation: Arq Bras Cardiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Sao Paulo : Sociedad Brasileira De Cardiologia
مواضيع طبية MeSH: Heart-Assist Devices*, Cardiomyopathies/*surgery , Heart Transplantation/*methods, Cardiomyopathies/mortality ; Child ; Child, Preschool ; Female ; Heart Transplantation/mortality ; Hemodynamics ; Hospitalization ; Humans ; Infant ; Male ; Postoperative Complications ; Retrospective Studies ; Severity of Illness Index ; Time Factors ; Treatment Outcome
مستخلص: Background: Heart transplantation is considered the gold standard therapy for the advanced heart failure, but donor shortage, especially in pediatric patients, is the main limitation for this procedure, so most sick patients die while waiting for the procedure.
Objective: To evaluate the use of short-term circulatory support as a bridge to transplantation in end-stage cardiomyopathy.
Methods: Retrospective clinical study. Between January 2011 and December 2013, 40 patients with cardiomyopathy were admitted in our Pediatric Intensive Care Unit, with a mean age of 4.5 years. Twenty patients evolved during hospitalization with clinical deterioration and were classified as Intermacs 1 and 2. One patient died within 24 hours and 19 could be stabilized and were listed. They were divided into 2 groups: A, clinical support alone and B, implantation of short-term circulatory support as bridge to transplantation additionally to clinical therapy.
Results: We used short-term mechanical circulatory support as a bridge to transplantation in 9. In group A (n=10), eight died waiting and 2 patients (20%) were transplanted, but none was discharged. In group B (n=9), 6 patients (66.7%) were transplanted and three were discharged.The mean support time was 21,8 days (6 to 984 h). The mean transplant waiting list time was 33,8 days. Renal failure and sepsis were the main complication and cause of death in group A while neurologic complications were more prevalent en group B.
Conclusion: Mechanical circulatory support increases survival on the pediatric heart transplantation waiting list in patients classified as Intermacs 1 and 2.
التعليقات: Comment in: Arq Bras Cardiol. 2016 Apr;106(4):350-1. (PMID: 27142798)
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تواريخ الأحداث: Date Created: 20141106 Date Completed: 20150727 Latest Revision: 20211021
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC4387614
DOI: 10.5935/abc.20140165
PMID: 25372474
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-4170
DOI:10.5935/abc.20140165