دورية أكاديمية

Subclinical hypercortisolism in central serous chorioretinopathy.

التفاصيل البيبلوغرافية
العنوان: Subclinical hypercortisolism in central serous chorioretinopathy.
المؤلفون: Appa SN; Department of Ophthalmology, Kaiser Permanente, Yorba Linda, California.
المصدر: Retinal cases & brief reports [Retin Cases Brief Rep] 2014 Fall; Vol. 8 (4), pp. 310-3.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101298744 Publication Model: Print Cited Medium: Internet ISSN: 1937-1578 (Electronic) Linking ISSN: 19351089 NLM ISO Abbreviation: Retin Cases Brief Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, MD : Wolters Kluwer Health, c2007-
مواضيع طبية MeSH: Adenoma/*complications , Central Serous Chorioretinopathy/*etiology , Cushing Syndrome/*complications , Pituitary Neoplasms/*complications, Adenoma/metabolism ; Adrenocorticotropic Hormone/metabolism ; Adult ; Chronic Disease ; Female ; Humans ; Pituitary Neoplasms/metabolism
مستخلص: Purpose: To describe a case of a patient with chronic central serous chorioretinopathy who was found to have an adrenocorticotropin-secreting pituitary microadenoma despite the absence of many clinical signs of Cushing syndrome.
Methods: A retrospective chart review was performed. This study included a 42-year-old white woman with a history of chronic central serous chorioretinopathy.
Results: The patient was found to have severe osteoporosis; although many of the classic signs of Cushing syndrome were absent, laboratory studies and neuroimaging suggested the presence of a pituitary microadenoma. Ophthalmic evaluation revealed the presence of bilateral submacular fluid because of chronic multifocal central serous chorioretinopathy. The patient underwent bilateral photodynamic therapy and surgical excision of the pituitary lesion. Pathologic evaluation confirmed that the pituitary lesion was a pituitary microadenoma.
Conclusion: Careful attention to the signs of hypercortisolism in patients with central serous chorioretinopathy may aid in detecting underlying systemic pathology. Endocrinology evaluations in patients presenting with any manifestations of Cushing syndrome may be warranted, even if many classic physical findings are absent.
المشرفين على المادة: 9002-60-2 (Adrenocorticotropic Hormone)
تواريخ الأحداث: Date Created: 20141106 Date Completed: 20150630 Latest Revision: 20181202
رمز التحديث: 20240829
DOI: 10.1097/ICB.0000000000000036
PMID: 25372535
قاعدة البيانات: MEDLINE
الوصف
تدمد:1937-1578
DOI:10.1097/ICB.0000000000000036