دورية أكاديمية
Internal capsule stroke in the common marmoset.
| العنوان: | Internal capsule stroke in the common marmoset. |
|---|---|
| المؤلفون: | Puentes S; Department of Neurophysiology, National Institute of Neuroscience, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan. Electronic address: sandra@ncnp.go.jp., Kaido T; Department of Neurosurgery, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8551, Japan. Electronic address: kaido@ncnp.go.jp., Hanakawa T; Department of Advanced Neuroimaging, Integrative Brain Image Center, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8551, Japan. Electronic address: hanakawa@ncnp.go.jp., Ichinohe N; Department of Ultrastructural Research, National Institute of Neuroscience, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan. Electronic address: nichino@ncnp.go.jp., Otsuki T; Department of Neurosurgery, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8551, Japan. Electronic address: otsukit@ncnp.go.jp., Seki K; Department of Neurophysiology, National Institute of Neuroscience, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan. Electronic address: seki@ncnp.go.jp. |
| المصدر: | Neuroscience [Neuroscience] 2015 Jan 22; Vol. 284, pp. 400-411. Date of Electronic Publication: 2014 Oct 20. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: [New York?] : Elsevier Science Original Publication: Oxford, Elmsford, N. Y., Pergamon Press |
| مواضيع طبية MeSH: | Callithrix*/anatomy & histology , Disease Models, Animal* , Internal Capsule*/blood supply , Internal Capsule*/pathology , Stroke*/pathology , Stroke*/physiopathology, Animals ; Cerebral Arteries/anatomy & histology ; Humans ; Magnetic Resonance Imaging ; Movement Disorders/physiopathology ; Neurosurgical Procedures ; Severity of Illness Index |
| مستخلص: | White matter (WM) impairment and motor deficit after stroke are directly related. However, WM injury mechanisms and their relation to motor disturbances are still poorly understood. In humans, the anterior choroidal artery (AChA) irrigates the internal capsule (IC), and stroke to this region can induce isolated motor impairment. The goal of this study was to analyze whether AChA occlusion can injure the IC in the marmoset monkey. The vascular distribution of the marmoset brain was examined by colored latex perfusion and revealed high resemblance to the human brain anatomy. Next, a new approach to electrocoagulate the AChA was developed and chronic experiments showed infarction compromising the IC on magnetic resonance imaging (MRI) scanning (day 4) and histology (day 11). Behavioral analysis was performed using a neurologic score previously developed and our own scoring method. Marmosets showed a decreased score that was still evident at day 10 after AChA electrocoagulation. We developed a new approach able to induce damage to the marmoset IC that may be useful for the detailed study of WM impairment and behavioral changes after stroke in the nonhuman primate. (Copyright © 2014 IBRO. Published by Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: anterior choroidal artery; internal capsule; motor impairment; nonhuman primate; white matter stroke |
| تواريخ الأحداث: | Date Created: 20141203 Date Completed: 20151222 Latest Revision: 20200725 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.neuroscience.2014.10.015 |
| PMID: | 25453768 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1873-7544 |
|---|---|
| DOI: | 10.1016/j.neuroscience.2014.10.015 |