دورية أكاديمية
Parvalbumin expression and distribution in the hippocampal formation of Cebus apella.
| العنوان: | Parvalbumin expression and distribution in the hippocampal formation of Cebus apella. |
|---|---|
| المؤلفون: | Torres LB; Universidade Federal de São Paulo, Unifesp/EPM, Departamento de Neurologia e Neurocirurgia, Laboratório de Neurociências, São Paulo, Brazil; Hospital Israelita Albert Einstein, Instituto do Cérebro, São Paulo, Brazil; Instituto Evandro Chagas (IEC), Centro Nacional de Primatas (CENP), Ananindeua, Brazil., Araujo BH, Marruaz KS, de Souza JS, Sousa BS, Gomes da Silva S, Cabral FR, Cavalheiro EA |
| المصدر: | American journal of primatology [Am J Primatol] 2015 Apr; Vol. 77 (4), pp. 449-61. Date of Electronic Publication: 2014 Dec 03. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8108949 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2345 (Electronic) Linking ISSN: 02752565 NLM ISO Abbreviation: Am J Primatol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York : Wiley-Blackwell Original Publication: New York : Liss, c1981- |
| مواضيع طبية MeSH: | Cebus/*metabolism , Hippocampus/*metabolism , Neurons/*metabolism , Parvalbumins/*metabolism, Animals ; Cebus/anatomy & histology ; Female ; Hippocampus/anatomy & histology ; Hippocampus/cytology ; Immunohistochemistry ; Interneurons/cytology ; Interneurons/metabolism ; Male ; Neurons/cytology |
| مستخلص: | New World primates play an important role in biomedical research. However, the literature still lacks information on many structural features of the brain in these species, particularly structures of the hippocampal formation that are related to long-term memory storage. This study was designed to provide information, for the first time, about the distribution and number of neurons expressing parvalbumin-immunoreactivity (PV-I) in the subregions of the hippocampal formation in Cebus apella, a New World primate species commonly used in biomedical research. Our results revealed that for several morphometric variables, PV-I cells differ significantly among the subregions CA1, CA2, CA3, and the hilus. Based upon our findings and those of other studies, we hypothesize that the proportional increase from monkeys to humans in PV-I cell density within CA1 is a factor contributing to the evolution of increased memory formation and storage. (© 2014 Wiley Periodicals, Inc.) |
| فهرسة مساهمة: | Keywords: CA2 layer; inhibitory interneurons; memory storage; new world primates; stereology |
| المشرفين على المادة: | 0 (Parvalbumins) |
| تواريخ الأحداث: | Date Created: 20141205 Date Completed: 20151026 Latest Revision: 20150324 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1002/ajp.22366 |
| PMID: | 25472893 |
| قاعدة البيانات: | MEDLINE |
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