التفاصيل البيبلوغرافية
العنوان: |
Personalization of loco-regional care for primary breast cancer patients (part 2). |
المؤلفون: |
Toi M; Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606-8507, Japan., Winer EP, Benson JR, Inamoto T, Forbes JF, von Minckwitz G, Robertson JF, Grobmyer SR, Jatoi I, Sasano H, Kunkler I, Ho AY, Yamauchi C, Chow LW, Huang CS, Han W, Noguchi S, Pegram MD, Yamauchi H, Lee ES, Larionov AA, Bevilacqua JL, Yoshimura M, Sugie T, Yamauchi A, Krop IE, Noh DY, Klimberg VS |
مؤلفون مشاركون: |
2014 Kyoto Breast Cancer Consensus Conference |
المصدر: |
Future oncology (London, England) [Future Oncol] 2015; Vol. 11 (9), pp. 1301-5. |
نوع المنشور: |
Journal Article; Research Support, Non-U.S. Gov't |
اللغة: |
English |
بيانات الدورية: |
Publisher: Future Medicine Ltd Country of Publication: England NLM ID: 101256629 Publication Model: Print Cited Medium: Internet ISSN: 1744-8301 (Electronic) Linking ISSN: 14796694 NLM ISO Abbreviation: Future Oncol Subsets: MEDLINE |
أسماء مطبوعة: |
Original Publication: London : Future Medicine Ltd., c2005- |
مواضيع طبية MeSH: |
Precision Medicine*, Breast Neoplasms/*diagnosis , Breast Neoplasms/*therapy, Disease Management ; Female ; Humans |
مستخلص: |
Kyoto Breast Cancer Consensus Conference, Kyoto, Japan, 18-20 February 2014 The loco-regional management of breast cancer is increasingly complex with application of primary systemic therapies, oncoplastic techniques and genetic testing for breast cancer susceptibility. Personalization of loco-regional treatment is integral to optimization of breast cancer care. Clinical and pathological tumor stage, biological features and host factors influence loco-regional treatment strategies and extent of surgical procedures. Key issues including axillary staging, axillary treatment, radiation therapy, primary systemic therapy (PST), preoperative hormonal therapy and genetic predisposition were identified and discussed at the Kyoto Breast Cancer Consensus Conference (KBCCC2014). In the second of a two part conference scene, consensus recommendations for radiation treatment, primary systemic therapies and management of genetic predisposition are reported and focus on the following topics: influence of both clinical response to PST and stage at presentation on recommendations for postmastectomy radiotherapy; use of regional nodal irradiation in selected node-positive patients and those with adverse pathological factors; extent of surgical resection following downstaging of tumors with PST; use of preoperative hormonal therapy in premenopausal women with larger, node-negative luminal A-like tumors and managing increasing demands for contralateral prophylactic mastectomy in patients with a unilateral sporadic breast cancer. |
فهرسة مساهمة: |
Keywords: BRCA1/2; breast cancer; luminal type; postmastectomy radiation therapy |
تواريخ الأحداث: |
Date Created: 20150509 Date Completed: 20160203 Latest Revision: 20150508 |
رمز التحديث: |
20221213 |
DOI: |
10.2217/fon.15.66 |
PMID: |
25952778 |
قاعدة البيانات: |
MEDLINE |