دورية أكاديمية
أعرض في EDS

Health-related quality of life and hospital costs following esophageal resection: a prospective cohort study.

التفاصيل البيبلوغرافية
العنوان: Health-related quality of life and hospital costs following esophageal resection: a prospective cohort study.
المؤلفون: Strik C; Department of surgery, Radboud University Medical Center, postal number 618, P.O. Box 9101, 6500, HB, Nijmegen, Netherlands. chema.strik@radboudumc.nl., ten Broek RP; Department of surgery, Radboud University Medical Center, postal number 618, P.O. Box 9101, 6500, HB, Nijmegen, Netherlands., van der Kolk M; Department of surgery, Radboud University Medical Center, postal number 618, P.O. Box 9101, 6500, HB, Nijmegen, Netherlands., van Goor H; Department of surgery, Radboud University Medical Center, postal number 618, P.O. Box 9101, 6500, HB, Nijmegen, Netherlands., Bonenkamp JJ; Department of surgery, Radboud University Medical Center, postal number 618, P.O. Box 9101, 6500, HB, Nijmegen, Netherlands.
المصدر: World journal of surgical oncology [World J Surg Oncol] 2015 Sep 04; Vol. 13, pp. 266. Date of Electronic Publication: 2015 Sep 04.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819 (Electronic) Linking ISSN: 14777819 NLM ISO Abbreviation: World J Surg Oncol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, 2003-
مواضيع طبية MeSH: Hospital Costs* , Quality of Life*, Adenocarcinoma/*economics , Esophageal Neoplasms/*economics , Laparoscopy/*economics , Laparotomy/*economics, Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Aged ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Female ; Follow-Up Studies ; Humans ; Length of Stay ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Prospective Studies
مستخلص: Background: The incidence rates for adenocarcinoma of the esophagus are increasing while the prognosis has only improved slightly. There is no apparent benefit in short- and long-term survival after different surgical strategies, but surgery is associated with significant morbidity. The goal of this study is to prospectively assess the quality of life and hospital costs after esophageal resections depending on the development of complications.
Methods: Prospective data was collected from 47 patients undergoing an esophageal resection for esophageal cancer participating in the prospective LAParotomy or LAParoscopy and Adhesions (LAPAD) study (clinicaltrials.gov registration number: NCT01236625). A comparison was made between patients who developed major complications and minor or no complications regarding quality of life and hospital costs.
Results: Thirteen patients developed major complications while 34 patients developed only minor or no complications. Patients with major complications had a mean hospital cost of $16,369 vs $12,409 for patients without or with minor complications. We found no difference in quality of life between the two groups 6 months after surgery.
Conclusions: In our cohort, major complications did not seem to have a detrimental effect on postoperative quality of life 6 months after surgery but they increased costs associated with esophageal resection.
References: Am J Cardiol. 1989 Sep 15;64(10):651-4. (PMID: 2782256)
N Engl J Med. 2002 Nov 21;347(21):1662-9. (PMID: 12444180)
Chest. 2006 Oct;130(4):1165-72. (PMID: 17035452)
CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90. (PMID: 21296855)
Ann Surg. 2002 Aug;236(2):177-83. (PMID: 12170022)
Ann Surg. 2007 Dec;246(6):992-1000; discussion 1000-1. (PMID: 18043101)
J Am Coll Surg. 2003 May;196(5):671-8. (PMID: 12742194)
Ann Surg. 2009 Aug;250(2):187-96. (PMID: 19638912)
Dig Dis Sci. 1988 Feb;33(2):129-34. (PMID: 3123181)
J Surg Oncol. 2004 Nov 1;88(2):71-7. (PMID: 15499604)
Ann Surg. 2013 Jul;258(1):98-106. (PMID: 23013804)
BMJ. 1992 Jul 18;305(6846):160-4. (PMID: 1285753)
J Gastrointest Surg. 2011 Sep;15(9):1497-9. (PMID: 21590458)
J Thorac Cardiovasc Surg. 2011 Jan;141(1):16-21. (PMID: 21047648)
Lancet. 2012 May 19;379(9829):1887-92. (PMID: 22552194)
Cancer. 2007 Aug 1;110(3):686-93. (PMID: 17582628)
Br J Surg. 1996 Dec;83(12):1772-5. (PMID: 9038566)
Lancet Oncol. 2005 Nov;6(11):864-70. (PMID: 16257794)
Eur J Cardiothorac Surg. 2011 Dec;40(6):1455-63; discussion 1463-4. (PMID: 21514837)
سلسلة جزيئية: ClinicalTrials.gov NCT01236625
تواريخ الأحداث: Date Created: 20150905 Date Completed: 20160609 Latest Revision: 20240520
رمز التحديث: 20240520
مُعرف محوري في PubMed: PMC4558724
DOI: 10.1186/s12957-015-0678-3
PMID: 26338109
قاعدة البيانات: MEDLINE
الوصف
تدمد:1477-7819
DOI:10.1186/s12957-015-0678-3