دورية أكاديمية
[Factors Affecting Outcomes of Repeated Penetrating Keratoplasty].
| العنوان: | [Factors Affecting Outcomes of Repeated Penetrating Keratoplasty]. |
|---|---|
| المؤلفون: | Yamamoto S, Shimmura-Tomita M, Satake Y, Shimazaki-Den S, Shimmura S, Shimazaki J |
| المصدر: | Nippon Ganka Gakkai zasshi [Nippon Ganka Gakkai Zasshi] 2015 Sep; Vol. 119 (9), pp. 625-31. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Japanese |
| بيانات الدورية: | Publisher: Nihon Ganka Gakkai Country of Publication: Japan NLM ID: 7505716 Publication Model: Print Cited Medium: Print ISSN: 0029-0203 (Print) Linking ISSN: 00290203 NLM ISO Abbreviation: Nippon Ganka Gakkai Zasshi Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Tokyo : Nihon Ganka Gakkai |
| مواضيع طبية MeSH: | Graft Rejection* , Graft Survival* , Keratoplasty, Penetrating*, Corneal Diseases/*surgery, Aged ; Cyclosporine/therapeutic use ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Male ; Middle Aged ; Prognosis ; Reoperation ; Retrospective Studies ; Treatment Outcome ; Visual Acuity |
| مستخلص: | Purpose: To investigate prognosis for repeated penetrating keratoplasty (PKP) and factors that affect the outcome. Methods: We retrospectively investigated graft survival rates, 1-year postoperative best-corrected visual acuity and irreversible rejection rates in 108 eyes of 106 patients that had repeated PKP. Factors that might affect the outcome were, age, number of previous PKP, original diseases, history of glaucoma and rejection and the use of postoperative immunosuppressant were also studied. Results: Individual-factor analysis showed that history of rejection and postoperative immunosuppressant significantly increased the risk of postoperative rejection. Multi-factor analysis showed that graft survival rate was significantly lower among cases that had systemic immunosuppressants (steroids and cyclosporine). One year postoperative best-corrected visual acuity was significantly worse in cases that had history of glaucoma. In cases with history of rejection, systemic administration of postoperative immunosuppressants was significantly associated with postoperative irreversible rejection. Conclusion: History of rejection and glaucoma tend to have poor outcome, and the outcome might not improve by postoperative immunosuppressants. |
| المشرفين على المادة: | 0 (Immunosuppressive Agents) 83HN0GTJ6D (Cyclosporine) |
| تواريخ الأحداث: | Date Created: 20151020 Date Completed: 20160201 Latest Revision: 20151019 |
| رمز التحديث: | 20231215 |
| PMID: | 26477068 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0029-0203 |
|---|