دورية أكاديمية

Reviewing the use of corticosteroids in bronchopulmonary dysplasia.

التفاصيل البيبلوغرافية
العنوان: Reviewing the use of corticosteroids in bronchopulmonary dysplasia.
المؤلفون: de Oliveira Peixoto FA; Department of Pediatrics, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia, GO, Brazil; Neonatal Intensive Care Unit (NICU), Hospital das Clínicas, Universidade Federal de Goiás (UFG), Goiânia, GO, Brazil. Electronic address: fernandapeixoto20@gmail.com., Costa PS; Department of Pediatrics, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia, GO, Brazil.
المصدر: Jornal de pediatria [J Pediatr (Rio J)] 2016 Mar-Apr; Vol. 92 (2), pp. 122-8. Date of Electronic Publication: 2015 Dec 20.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Elsevier Editora Ltda Country of Publication: Brazil NLM ID: 2985188R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4782 (Electronic) Linking ISSN: 00217557 NLM ISO Abbreviation: J Pediatr (Rio J) Subsets: MEDLINE
أسماء مطبوعة: Publication: Rio de Janeiro, Brazil : Elsevier Editora Ltda
Original Publication: Rio de Janeiro.
مواضيع طبية MeSH: Adrenal Cortex Hormones/*administration & dosage , Adrenal Cortex Hormones/*adverse effects , Bronchopulmonary Dysplasia/*drug therapy , Infant, Premature, Diseases/*drug therapy, Humans ; Infant, Newborn ; Risk Factors
مستخلص: Objective: Review the risks and benefits of postnatal corticosteroid use for the treatment of bronchopulmonary dysplasia, considering that there is not a more effective therapy.
Data Sources: The literature review was carried out in the BIREME database, using the terms "bronchopulmonary dysplasia and corticosteroid" in the LILACS, IBECS, MEDLINE, Cochrane Library, and SciELO databases, selecting the most relevant articles on the subject, with emphasis on recent literature published in the last five years.
Summary of the Data: In preterm infants, bronchopulmonary dysplasia is still a common problem and remains without a specific therapy, despite knowledge of the several risk factors. The treatment essentially consists of supportive measures, but in the past, corticosteroids were widely used, as they are the only medications that have an impact on disease progression. However, the emergence of cerebral palsy associated with the indiscriminate use of corticosteroids has prevented the prescription of this drug in the last 15 years. Since then, no new measures have been taken, and the incidence of the disease tended to increase during this period, creating the need for a review of corticosteroid use and, possibly, more restricted indications.
Conclusions: The association between risks and benefits of corticosteroid use in preterm infants needs to be considered due to the fact that some infant subpopulations may show more benefits than risks, such as those using mechanical ventilation with difficult weaning.
(Copyright © 2015 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.)
فهرسة مساهمة: Keywords: Bronchopulmonary dysplasia; Corticoide; Corticosteroids; Displasia broncopulmonar; Tratamento; Treatment
المشرفين على المادة: 0 (Adrenal Cortex Hormones)
تواريخ الأحداث: Date Created: 20151229 Date Completed: 20161213 Latest Revision: 20220309
رمز التحديث: 20231215
DOI: 10.1016/j.jped.2015.07.007
PMID: 26709507
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-4782
DOI:10.1016/j.jped.2015.07.007